Cardiac06 / 22
Unrepaired VSD for adenotonsillectomy4-year-old boy, 13 kg, for elective adenotonsillectomy
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Know this first
- A Qp:Qs over 1.5:1 means pulmonary blood flow must be managed.
- Air in any IV line can cross a shunt to the systemic side.
- Endocarditis prophylaxis is for the highest-risk groups, not an unrepaired acyanotic VSD.
- Laryngospasm: CPAP and propofol, then suxamethonium 1–2 mg/kg IV or 4–5 mg/kg IM.
The patient
4-year-old boy, 13 kg, for elective adenotonsillectomy; loud snoring with witnessed apnoeas.
Unrepaired moderate perimembranous VSD, left-to-right, Qp:Qs 1.8:1; weight below the 5th centile.
No regular drugs; no pulmonary hypertension on last echo.
Vitals: HR 118, BP 94/52, SpO2 98% on air, RR 26.
The examiner asks
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Consider
What are the issues?
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- A 4-year-old with an unrepaired moderate VSD and apnoeas, for adenotonsillectomy. Patient
- As a young child his output depends on heart rate, so bradycardia is poorly tolerated.
- His shunt is left-to-right at 1.8:1, so I limit extra pulmonary flow. Disease
- His poor growth makes me ask about sweating, fast breathing, poor feeding and chest infections.
- Witnessed apnoeas mean obstructive sleep apnoea, with obstruction and desaturation after surgery. Surgery
Prepare
How will you prepare?
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- Recent echo for his shunt size, direction and pulmonary pressure. Disease
- No endocarditis prophylaxis: his unrepaired acyanotic VSD isn't a highest-risk lesion.
- Every IV line and syringe de-aired before it reaches him.
- Oral midazolam 0.2–0.5 mg/kg so he arrives settled. Patient
- Overnight stay with oximetry until he holds his saturation on air while asleep. After surgery
Plan
How do you conduct the anaesthetic?
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- Gas induction with sevoflurane, then IV access; his shunt barely changes the speed. Disease
- No high oxygen or hyperventilation, which lower PVR and increase his shunt.
- Avoid sharp rises in systemic resistance from light anaesthesia or pain.
- Suction blood from his pharynx before extubation; blood triggers laryngospasm. Airway
- Dexamethasone 0.15 mg/kg, ondansetron 50–100 mcg/kg, paracetamol 15 mg/kg IV. After surgery
- OSA makes him opioid-sensitive, so I halve his opioid doses. Disease
Crisis
At extubation he develops laryngospasm; SpO2 falls to 70% and HR to 58. What do you do?
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- Laryngospasm with hypoxic bradycardia, HR 58: PALS bradycardia, and airway first. (Crisis)
- Call for help; tight mask, 100% oxygen, CPAP 15–20 cmH2O, firm jaw thrust.
- SpO2 70% already: suxamethonium 1–2 mg/kg IV, or 4–5 mg/kg IM.
- His slow rate is hypoxic, so oxygen is the treatment; atropine 0.02 mg/kg goes with the suxamethonium.
- Hypoxia also raises his PVR and can reverse flow across his VSD.
- HR still under 60 and poorly perfused despite good ventilation: start CPR.
- Bradycardia persisting once oxygenated: adrenaline 0.01 mg/kg IV.
Fatal mistakes
- Air in his IV lines.
- Slow, stepwise hesitation in treating laryngospasm.
- No drug plan for hypoxic bradycardia.
- Sending him home the same day.
Checked against: Stoelting 8e · Barash 9e · AHA and AAP guidelines: pediatric advanced life support (2025)
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