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Intra-operative crises · Core21 / 21

Bone cement implantation syndrome with aortic stenosis86-year-old woman, 52 kg, frail; displaced intracapsular hip fracture

Bone cement implantation syndrome: RV failure at cementing in a frail patient

From memory: the diagnosis and the notes are hidden. Answer each question aloud, then press Show.

Know this first

  • BCIS: hypotension, hypoxia, arrhythmia, raised PVR, RV failure or arrest at cementing.
  • Risk: increasing age, diuretics, cardiopulmonary disease, male sex, metastases, long-stem prosthesis.
  • Keep systolic within 20% of baseline; invasive BP for higher-risk patients.
  • Aortic stenosis: preload and afterload maintained, sinus rhythm, no tachycardia.
  • Treatment is supportive: oxygen, fluid, vasopressors, adrenaline for the RV.

The patient

86-year-old woman, 52 kg, frail; displaced intracapsular hip fracture. Moderate aortic stenosis on a recent echo; sinus rhythm. Drugs: furosemide. Cemented hemiarthroplasty on the next trauma list. Vitals: BP 138/70, HR 82, SpO2 94% on air, RR 18.

The examiner asks

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  1. Consider

    What are your concerns?

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    • An 86-year-old frail woman with moderate aortic stenosis, for cemented hemiarthroplasty. Patient
    • At 86 and frail, I check her cognition and baseline; delirium risk is high.
    • Her BCIS risks: age, diuretic use, and significant heart disease. Disease
    • Her valve needs preload and afterload kept up, sinus rhythm, and no tachycardia.
    • Cementing pressurises the canal; marrow emboli raise PVR and can fail her RV. Surgery
    • For high-risk patients an uncemented stem is an option; I raise it with the surgeon.
  2. Prepare

    How do you prepare for cementing?

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    • Agreed call: surgeon announces cementing, and I confirm I've heard. Surgery
    • Surgeon washes and dries the canal, vents it, guns the cement and avoids excess pressure.
    • Arterial line before induction, given her valve and BCIS risk. Disease
    • Well filled before induction; her furosemide leaves her dry.
    • Systolic held within 20% of her baseline with fluid and vasopressor.
    • Noradrenaline and adrenaline ready before cementing; phenylephrine 50–100 mcg for induction dips. Crisis
    • Her ceiling of care agreed with her and her family before theatre. After surgery
  3. Crisis

    As the cement goes in, SpO2 falls to 85%, BP to 68/40, HR 112. What do you do?

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    • BCIS at cementing: surgeon told, help called. Crisis
    • 100% oxygen and ventilation supported.
    • Noradrenaline or adrenaline first, noradrenaline from 0.05–0.1 mcg/kg/min; phenylephrine only if the RV looks well.
    • Not responding: adrenaline to support her failing right ventricle.
    • Fluid bolus, judged against how distended her RV looks.
    • Tachycardia raises her heart's oxygen demand; restoring pressure is the fix. Disease
  4. Crisis

    BP becomes unrecordable; the arterial trace is flat and the ECG shows sinus rhythm at 50. What now?

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    • Adult arrest algorithm: PEA, non-shockable, from BCIS and RV failure. Crisis
    • CPR now, turning her supine; adrenaline 1 mg IV without delay.
    • Then adrenaline 1 mg every 3–5 minutes.
    • Reversible causes in her: pulmonary embolism of marrow and cement, bleeding, hypoxia.
    • Echo if available, to see her RV and look for tamponade or an empty heart.
    • After ROSC: ICU, and her family told. After surgery

Fatal mistakes

  • No warning or communication before cementing.
  • Accepting hypotension in aortic stenosis.
  • Inadequate support for a failing right ventricle.
  • Fluid loading alone into a dilated RV.

Checked against: Anaesthesia for hip fracture repair (2020) · Miller 10e · Barash 9e

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