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COPD with CO2 retention for laparoscopic fundoplication74-year-old man, 70 kg, for elective laparoscopic fundoplication of a large hiatus hernia with reflux

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Know this first

  • At 15 mmHg intra-abdominal pressure the IVC is compressed and cardiac output falls.
  • In COPD, end-tidal CO2 underestimates PaCO2 because physiological dead space is wide.
  • Fundoplication, near the diaphragm, carries the highest risk of surgical emphysema and capnothorax.
  • Capnothorax: release the pneumoperitoneum first; needle or drain if he stays unstable.

The patient

74-year-old man, 70 kg, for elective laparoscopic fundoplication of a large hiatus hernia with reflux. Moderate COPD after 50 pack-years; breathless after one flight of stairs; serum bicarbonate 32 mmol/L. Drugs: tiotropium, salbutamol inhaler, omeprazole. Vitals: BP 146/84, HR 84, SpO2 92% on air, RR 18. PaCO2 52 mmHg on air.

The examiner asks

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  1. Consider

    What are your concerns?

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    • A 74-year-old with moderate COPD and CO2 retention, for elective laparoscopic fundoplication. Patient
    • At 74, his age and a hiatal operation both raise his risk of surgical emphysema.
    • His bicarbonate of 32 points to chronic CO2 retention; his gas confirms a PaCO2 of 52. Disease
    • Pneumoperitoneum releases catecholamines and vasopressin, raising his afterload; at 15 mmHg his venous return falls. Surgery
    • The diaphragm rises: his compliance falls, airway pressure rises and his bases collapse.
    • Absorbed CO2 can push his PaCO2 up fast, beyond what extra ventilation can clear. Disease
  2. Prepare

    How will you prepare him?

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    • Tiotropium and his inhalers continue on the morning of surgery. Disease
    • Salbutamol 2–4 puffs, 20–30 minutes before I handle his airway.
    • His baseline gas on air tells me which PaCO2 is normal for him.
    • I ask the surgeon for the lowest insufflation pressure that still gives a view. Surgery
    • HDU bed booked, since he may need breathing support afterwards. After surgery
  3. Plan

    How will you ventilate him?

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    • 6–8 mL/kg ideal-weight breaths, with PEEP 5–10 cmH2O. Disease
    • Long expiratory time; his compliant emphysematous lungs need longer to empty.
    • Auto-PEEP grows with bigger breaths and shorter expiry, and the ventilator gauge won't show it.
    • I accept a mildly raised CO2 rather than chase it with fast, large breaths.
    • Arterial line for gases, because his end-tidal reads below his true PaCO2.
    • Head-up tilt pools blood in his legs, so I watch his pressure as he tilts. Surgery
    • Insufflation pushes the carina up; I recheck his tube position afterwards. Airway
  4. Crisis

    Forty minutes in, end-tidal CO2 climbs from 45 to 68 mmHg and his neck and chest crackle. BP 150/90, HR 104, SpO2 94%. What do you do?

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    • Surgical emphysema: CO2 is tracking outside the peritoneum, as fundoplication invites. Crisis
    • Tell the surgeon, lower the pressure, and mark how far the crackling spreads.
    • More ventilation within his limits; if CO2 keeps rising, the abdomen is deflated.
    • Arterial gas now, since his end-tidal underestimates the real PaCO2.
    • If surgery must go on, reinsufflation at a lower pressure.
    • Neck emphysema: chest X-ray, and his airway checked for obstruction before extubation. After surgery
  5. Crisis

    Minutes later, peak airway pressure is 42 cmH2O, SpO2 84%, BP 70/40. What now?

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    • Tension capnothorax until proven otherwise; his hiatus opens into the chest. Crisis
    • Pneumoperitoneum released now, 100% oxygen, and the surgeon told.
    • I listen and watch both sides move, and exclude his tube slipping into a bronchus.
    • Fluids and a vasopressor while it settles; PEEP reduces the abdomen-to-chest gradient.
    • Still unstable after deflation: I decompress with a needle, then a drain goes in.
    • If it recurs on reinsufflation, the case converts to open; ICU afterwards. After surgery

Fatal mistakes

  • Keeping the abdomen insufflated while he has tension physiology.
  • Driving high minute ventilation until his lungs trap gas and his pressure falls.
  • Missing a tube pushed into a main bronchus by the rising diaphragm.

Checked against: Barash 9e · Miller 10e · The European Association for Endoscopic Surgery clinical practice guideline on the pneumoperitoneum for laparoscopic surgery (2002)

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