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Obstetric anaesthesia12 / 17

Anterior mediastinal mass at term for caesarean26-year-old woman, 62 kg, at 37 weeks; anterior mediastinal mass found 2 weeks ago

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Know this first

  • Supine breathlessness or cough warns of airway obstruction at induction.
  • Over 50% tracheal compression on CT raises risk.
  • Rigid bronchoscope and surgeon present; keep spontaneous breathing.
  • Bypass 'standby' is too slow; cannulate before induction if GA is unavoidable.
  • First rescues: change position, or rigid bronchoscopy past the obstruction.

The patient

26-year-old woman, 62 kg, at 37 weeks; anterior mediastinal mass found 2 weeks ago, probably lymphoma; no tissue diagnosis yet. Breathless lying flat, sleeps on three pillows; facial swelling and distended neck veins. No regular drugs. Planned caesarean delivery before oncology treatment. Vitals (sitting): BP 112/70, HR 104, SpO2 96% on air, RR 22.

The examiner asks

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  1. Consider

    What are your concerns?

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    • A 26-year-old at 37 weeks with an undiagnosed anterior mediastinal mass, for planned caesarean. Patient
    • Term pregnancy adds caval compression, small FRC and a difficult airway to her mass.
    • Orthopnoea warns that her airway may collapse at induction, possibly beyond any tube. Disease
    • Facial swelling and full neck veins mean superior vena cava obstruction.
  2. Prepare

    How will you assess her?

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    • Exactly which positions worsen or ease her breathing, and any faintness lying back. (Disease)
    • CT of trachea and chest: over 50% tracheal compression marks high risk.
    • Echo for pericardial effusion and compression of her heart or great vessels.
    • Can tissue come from somewhere under local anaesthesia, like a neck node or effusion?
  3. Prepare

    How do you prepare for the caesarean?

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    • Joint plan: obstetrics, thoracic surgery, oncology, cardiac anaesthesia, ICU and neonates. Patient
    • Rigid bronchoscope and a surgeon able to use it in the room from the start. Airway
    • A cannula in her leg as well as her arm, because her SVC is obstructed. Disease
    • Femoral cannulas or wires placed under local first, so ECMO can start fast; bypass 'standby' alone is too slow.
  4. Plan

    What is your anaesthetic plan?

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    • No general if possible: low-dose sequential CSE, or an epidural titrated slowly to T4. Disease
    • Semi-sitting in her best position, with left uterine displacement; she is never laid flat. Patient
    • Gradual onset keeps the fall in venous return slow. Disease
    • No sedation that depresses her breathing; nasal oxygen throughout. Airway
    • Neonatal team present; HDU after, since adults often obstruct in recovery. After surgery
  5. Crisis

    As the block rises she becomes stridulous and agitated; SpO2 86%, BP 88/50, HR 128, and the wound bleeds heavily. What do you do?

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    • Sit her further up or turn her to her best position: that's the first rescue. (Crisis)
    • 100% oxygen; she keeps breathing on her own, no relaxant.
    • Obstetrician delivers now; emptying the uterus relieves her caval compression.
    • Persisting obstruction: the surgeon passes a rigid bronchoscope beyond the narrowing.
    • Fluid and blood through the leg cannula; arm infusions may not reach her heart.
    • If she arrests: CPR with uterine displacement, deliver now; ECMO only via femoral access placed beforehand.

Fatal mistakes

  • Supine general anaesthesia with a muscle relaxant.
  • Venous access only in the arms with SVC obstruction.
  • No planned rescue position before starting.

Checked against: Miller 10e · Barash 9e

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