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Obstetric anaesthesia06 / 17

Preterm twins for caesarean under spinal28-year-old woman, 74 kg, with a dichorionic twin pregnancy at 34 weeks; first twin breech

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Know this first

  • Twins raise cardiac output about 20% more than a singleton.
  • Multiple gestation is a risk factor for atony.
  • Phenylephrine infusion starting 25–50 mcg/min prevents spinal hypotension.
  • Oxytocin 1–3 IU IV slowly, then 2.5–15 IU/h.
  • Carboprost 0.25 mg IM; caution in asthma. Methylergonovine 0.2 mg IM; avoid in hypertension.

The patient

28-year-old woman, 74 kg, with a dichorionic twin pregnancy at 34 weeks; first twin breech. In early preterm labour; mild anaemia, Hb 10.2 g/dL; antenatal steroids completed. Drugs: oral iron; betamethasone 12 mg IM, two doses given. Semi-urgent caesarean (category 2) under spinal. Vitals: BP 112/68, HR 96, SpO2 98% on air, RR 18.

The examiner asks

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  1. Consider

    What are your considerations?

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    • A 28-year-old with preterm twins at 34 weeks, first breech, for category 2 caesarean under spinal. Patient
    • Twins exaggerate pregnancy: her cardiac output rises about 20% more than with one baby.
    • Her large uterus compresses the cava when supine, so spinal hypotension is likely. Disease
    • Twins and anaemia make atony and haemorrhage more likely for her.
    • Two preterm babies: steroids are done, and each twin needs its own neonatal team. After surgery
  2. Prepare

    How do you prepare her?

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    • Two large-bore cannulas and a crossmatch, given her anaemia and bleeding risk. Patient
    • Sodium citrate 15–30 mL within the hour, and a wedge for left uterine displacement.
    • Phenylephrine infusion from the start at 25–50 mcg/min, with a crystalloid co-load. Disease
    • Oxytocin, carboprost, methylergonovine and tranexamic acid ready before incision.
  3. Plan

    What is your anaesthetic plan?

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    • Spinal: hyperbaric bupivacaine 10–12 mg, fentanyl 10–25 mcg and preservative-free morphine 0.1–0.2 mg. Disease
    • Block checked to T4 before the surgeon starts.
    • Her BP cycled every 1–3 minutes through the first 20 minutes.
    • After delivery, oxytocin 1–3 IU IV slowly, then 2.5–15 IU/h by infusion. After surgery
    • Both neonatal teams ready; the second twin may need help at birth.
  4. Crisis

    Five minutes after the spinal she feels sick, her hands tingle, and the block is at T2. BP 78/40, HR 52. What do you do?

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    • High block with hypotension and bradycardia: call for help, increase her tilt, raise her legs. (Crisis)
    • With HR 52, ephedrine boluses, not phenylephrine, and fluid running fast.
    • Glycopyrrolate 0.1–0.2 mg IV; adrenaline 2–10 mcg/min if she stays slow and low.
    • Phenylephrine only once her heart rate has recovered.
    • Her nausea is from low pressure; restoring it treats the nausea.
    • Check breathing, voice and grip; a weak voice means the block is climbing.
    • Intubate if she can't speak, ventilate, or loses consciousness.
  5. Crisis

    After both babies, the uterus is boggy; blood loss 1500 mL. BP 86/50, HR 124. What do you do?

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    • Atonic PPH: major haemorrhage call, obstetrician compressing the uterus. Crisis
    • Oxytocin infusion increased to 18–36 IU/h.
    • Carboprost 0.25 mg IM, repeat every 15–60 minutes; caution if she's asthmatic.
    • Methylergonovine 0.2 mg IM, as she isn't hypertensive.
    • Tranexamic acid 1 g, run over 10 minutes; we're inside the 3-hour window after birth.
    • Blood and fibrinogen early; balloon, compression sutures or hysterectomy if drugs fail.
    • HDU afterwards with close watch on bleeding and urine output. After surgery

Fatal mistakes

  • No uterotonic plan for atony after twins.
  • A single small cannula in a twin caesarean.
  • Treating spinal hypotension with fluid alone.

Checked against: Stoelting 8e · Barash 9e · Miller 10e

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