Active URI and asthma for MRI under GA3-year-old boy, 15 kg, for elective MRI brain under general anaesthesia in the radiology suite
Child with a cold: proceed or postpone, laryngospasm and paediatric bradycardia
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Know this first
- Fever, productive cough or purulent nasal discharge mark a significant URI with more airway events.
- Asthma, smoke exposure and airway instrumentation each add to that risk.
- About 2 weeks after symptoms settle is enough; a fixed 6-week wait isn't needed.
- Laryngospasm: 100% oxygen with CPAP 15–20 cmH2O, propofol, then suxamethonium.
- Pulse below 60 and poorly perfused after oxygen and ventilation: begin CPR.
The patient
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Consider
What are your concerns?
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- A feverish 3-year-old with a cold and asthma, booked for elective MRI under general anaesthesia. Patient
- At 3 he uses more oxygen per kilo than an adult, so he desaturates fast in any airway event.
- Fever, green discharge and wheeze make this a significant URI with a high airway-event risk. Disease
- His asthma and his father's smoking each add to that risk.
- MRI is remote: monitoring lags, nothing ferromagnetic near the magnet, and help is far away. Surgery
Prepare
Do you go ahead today?
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- No: an elective scan in a febrile child with green discharge and wheeze, so I postpone. Stem trigger
- Rebook about two weeks after his symptoms settle; six weeks isn't required.
- He keeps using his budesonide meanwhile, and comes back with a clear chest. Disease
- If the scan were urgent, an experienced paediatric anaesthetist would give it, as experience lowers airway events. Stem trigger
Plan
Three weeks later he is well and his chest is clear. How do you anaesthetise him?
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- Inhaled salbutamol before induction; it prevents bronchospasm in reactive children like him. Disease
- Oral midazolam 0.2–0.5 mg/kg so he is settled for a cannula. Patient
- Propofol IV induction, up to 3 mg/kg in a child; fewer airway events than gas. Airway
- Laryngeal mask rather than a tube, which lowers his respiratory complications.
- MR-safe monitor, pumps and machine; I expect the capnograph to lag in the scanner. Surgery
- Propofol, adrenaline, atropine and suxamethonium drawn up before he goes into the scanner. Crisis
- Mask removed awake: deep removal means less coughing but more obstruction, far from help. Airway
Crisis
In the MRI recovery bay, as the laryngeal mask comes out, he has stridor then silence; SpO2 82%. What do you do?
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- Laryngospasm: call for help; tight mask, 100% oxygen, CPAP 15–20 cmH2O and a firm jaw thrust. (Crisis)
- Suction his pharynx if secretions or blood set it off.
- Not breaking: propofol 1–2 mg/kg IV to deepen him.
- Still complete with falling saturation: suxamethonium 1–2 mg/kg IV, or 4–5 mg/kg IM without a cannula.
- Then mask-ventilate until he breathes, and check his chest for bronchospasm.
Crisis
Before the relaxant works, SpO2 is 60% and HR falls to 50 with weak pulses. What now?
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- PALS bradycardia with a pulse: HR 50 and poor perfusion, caused by his hypoxia. Crisis
- Oxygenation first: 100% oxygen and effective bag-mask ventilation; intubate if the mask fails.
- If his rate stays below 60 and he's poorly perfused despite good ventilation: CPR.
- Bradycardia persisting once oxygenated: adrenaline 0.01 mg/kg IV.
- Atropine 0.02 mg/kg only for a vagal cause, such as suxamethonium; it won't fix hypoxic bradycardia.
- Once recovered, he stays on oximetry in recovery until fully awake. After surgery
Fatal mistakes
- Going ahead with an elective scan in a febrile child with green discharge and wheeze.
- Atropine instead of oxygen and ventilation for his hypoxic bradycardia.
- Persisting with CPAP alone while saturation and heart rate fall.
- Anaesthesia in MRI without suction, a skilled assistant or MR-safe kit.
Checked against: Miller 10e · Stoelting 8e · Barash 9e · AHA and AAP guidelines: pediatric advanced life support (2025)
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