Bronchopleural fistula with empyema after lobectomy71-year-old man, 56 kg, three weeks after right lower lobectomy
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Know this first
- Three hazards: soiling the healthy lung, tension pneumothorax, and ventilation lost through the fistula.
- Continuous bubbling in the drain means a large fistula.
- Lung isolation is confirmed before positive pressure or turning.
- A double-lumen tube allows suction and protects the healthy lung.
The patient
The examiner asks
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Consider
What are your concerns?
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- A 71-year-old with a bronchopleural fistula, empyema and sepsis, for urgent rethoracotomy and repair. Patient
- At 71, septic and 7 kg lighter, he has little reserve; I record his baseline cognition for delirium.
- Air leak, fever and pus after lobectomy point to a fistula. Disease
- Three risks: pus soiling his left lung, tension pneumothorax, and breaths lost through the fistula.
- His leak bubbles continuously, so the fistula is large.
Prepare
How do you prepare him?
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- Sepsis first: antibiotics within the hour, cultures, and crystalloid at 30 mL/kg within three hours. Disease
- Noradrenaline at 0.05–0.5 mcg/kg/min if he stays hypotensive after fluid; arterial line before induction.
- His drain stays in and open; it protects him from tension pneumothorax under positive pressure.
- No thoracic epidural while he's septic; paravertebral by the surgeon or systemic analgesia instead.
- He sits up, leaning to the right, so pus stays in the infected side. Airway
Plan
How will you secure his airway?
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- Lung isolation before any positive pressure or turning; that is the rule here. Airway
- Left-sided double-lumen tube: it seals the healthy left lung away from the right stump.
- Safest is awake fibreoptic placement, if he can cooperate with topical anaesthesia.
- Otherwise a gas or titrated induction, keeping him breathing until the left lumen is sealed.
- Bronchoscope confirms the tube position, then again after he is turned.
- Small breaths at low airway pressure to the left lung once isolated. Disease
Crisis
During laryngoscopy he coughs up pus; SpO2 falls to 80%, BP 88/50. What do you do?
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- Pus is soiling his left lung: stay head-up, suction the airway, 100% oxygen. Crisis
- Place the left double-lumen tube now and inflate the bronchial cuff to seal the left lung.
- Suction down the left lumen, then bronchoscopic toilet and position check.
- Ventilate only the left lung, gently; the right lumen stays open to drain.
- No turning until the left lung is clean and isolation is proven.
- Expect pneumonitis in the left lung; ICU ventilation if his gas exchange stays poor. After surgery
Crisis
Once he is turned, the ventilator delivers 450 mL but only 150 mL returns; SpO2 85%. What do you do?
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- Two thirds of each breath is leaving through the fistula: bronchoscope first to check the tube. Crisis
- Turning can shift the tube; I reposition it so only the left lung is ventilated.
- Small breaths and low pressures; I accept a higher CO2 rather than force the leak.
- Never clamp his drain: a blocked drain turns this leak into a tension pneumothorax.
- Still failing: high-frequency ventilation lowers peak pressure and may cut the fistula leak.
- Extubate early after repair to spare the stump; otherwise ICU, then early extubation. After surgery
Fatal mistakes
- Positive-pressure ventilation before the fistula side is isolated.
- Clamping the chest drain.
- Turning him with the healthy lung dependent before isolation.
- Thoracic epidural in a septic patient.
Checked against: Miller 10e · Surviving Sepsis Campaign: international guidelines for sepsis and septic shock (2021)
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