Acute limb ischaemia from embolism for embolectomy82-year-old woman, 58 kg, for emergency right femoral embolectomy; cold, pale
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Know this first
- Limb outcome depends on how fast flow is restored.
- Neuraxial block on therapeutic heparin risks spinal haematoma.
- Reperfusion releases potassium and acid.
- Hyperkalaemia ECG: peaked T, wide QRS, then sine wave.
The patient
The examiner asks
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Consider
What are your concerns?
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- An 82-year-old with AF and heart failure, for emergency embolectomy of an acutely ischaemic leg. Patient
- At 82 with heart failure and an ischaemic leg, delirium is likely; I note her baseline cognition.
- Time-critical: the limb's outcome depends on how fast flow returns. Stem trigger
- ACC/AHA: emergency surgery, so straight to theatre; her failure and AF shape the anaesthetic. Disease
- Her potassium is already 5.1, with reperfusion still to come.
Prepare
What anaesthetic will you choose?
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- No spinal or epidural on therapeutic heparin; the haematoma risk is too high. Disease
- Femoral exposure can be done under local infiltration, sparing her failing heart. Surgery
- Surgeon's lidocaine within 4.5 mg/kg plain; propofol sedation 25–75 mcg/kg/min if needed.
- Bisoprolol continues; arterial line under local for beat-to-beat pressure. Disease
- Calcium chloride, insulin and glucose drawn up before the clot comes out.
Plan
How do you manage her through reperfusion?
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- If general anaesthesia is needed: etomidate 0.15–0.2 mg/kg and rocuronium. Airway
- No suxamethonium: it raises potassium by about 0.5 mmol/L. Disease
- Surgeon warns me before flow returns; I watch the ECG and send a gas.
- Reperfusion washes out acid and potassium from the ischaemic leg.
- Dark urine means myoglobin: fluids and bicarbonate to alkalinise the urine. After surgery
- A tense calf after reperfusion means compartment syndrome and urgent fasciotomy.
- Heparin resumes after surgery to stop the clot propagating.
Crisis
As flow returns, T waves become peaked and the QRS broadens; HR falls to 42, BP 84/50. What do you do?
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- Bradycardia algorithm with a clear cause: hyperkalaemia on reperfusion, slow and hypotensive. (Crisis)
- Treat the cause first: calcium chloride 500–1000 mg IV over 3 minutes.
- Insulin 10 units with 50 g glucose IV.
- Sodium bicarbonate for her acidosis, which also lowers potassium.
- Still slow: atropine 1 mg every 3–5 minutes, up to 3 mg.
- No response: adrenaline 2–10 mcg/min or transcutaneous pacing.
Crisis
Minutes later the ECG becomes a broad sine wave and she has no pulse. What do you do?
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- Adult arrest algorithm: PEA with a sine wave from hyperkalaemia; CPR started now. Crisis
- Non-shockable rhythm: give adrenaline 1 mg straight away, repeating every 3–5 minutes.
- Insulin-glucose, with calcium and bicarbonate considered; benefit in arrest is uncertain.
- Shock at once if it turns into VF.
- Other causes for her: acidosis, bleeding into the wound, and hypoxia.
- After return of circulation: ICU, repeated potassium and limb checks. After surgery
Fatal mistakes
- Spinal or epidural on therapeutic heparin.
- Missing hyperkalaemia on reperfusion.
- Suxamethonium with a raised potassium.
- Delaying revascularisation of the limb.
Checked against: Stoelting 8e · Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: ASRA Pain Medicine evidence-based guidelines (fifth edition) (2025) · AHA guidelines: special circumstances of resuscitation (2025) · Miller 10e · Faust
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