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Acute limb ischaemia from embolism for embolectomy82-year-old woman, 58 kg, for emergency right femoral embolectomy; cold, pale

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Know this first

  • Limb outcome depends on how fast flow is restored.
  • Neuraxial block on therapeutic heparin risks spinal haematoma.
  • Reperfusion releases potassium and acid.
  • Hyperkalaemia ECG: peaked T, wide QRS, then sine wave.

The patient

82-year-old woman, 58 kg, for emergency right femoral embolectomy; cold, pale, numb leg for 5 hours. Permanent AF, heart failure with EF 35%, chronic kidney disease, creatinine 1.6 mg/dL. Drugs: unfractionated heparin infusion at therapeutic range, bisoprolol, furosemide. Vitals: BP 146/84, HR 108 AF, SpO2 95% on air, RR 18. K+ 5.1 mmol/L.

The examiner asks

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  1. Consider

    What are your concerns?

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    • An 82-year-old with AF and heart failure, for emergency embolectomy of an acutely ischaemic leg. Patient
    • At 82 with heart failure and an ischaemic leg, delirium is likely; I note her baseline cognition.
    • Time-critical: the limb's outcome depends on how fast flow returns. Stem trigger
    • ACC/AHA: emergency surgery, so straight to theatre; her failure and AF shape the anaesthetic. Disease
    • Her potassium is already 5.1, with reperfusion still to come.
  2. Prepare

    What anaesthetic will you choose?

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    • No spinal or epidural on therapeutic heparin; the haematoma risk is too high. Disease
    • Femoral exposure can be done under local infiltration, sparing her failing heart. Surgery
    • Surgeon's lidocaine within 4.5 mg/kg plain; propofol sedation 25–75 mcg/kg/min if needed.
    • Bisoprolol continues; arterial line under local for beat-to-beat pressure. Disease
    • Calcium chloride, insulin and glucose drawn up before the clot comes out.
  3. Plan

    How do you manage her through reperfusion?

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    • If general anaesthesia is needed: etomidate 0.15–0.2 mg/kg and rocuronium. Airway
    • No suxamethonium: it raises potassium by about 0.5 mmol/L. Disease
    • Surgeon warns me before flow returns; I watch the ECG and send a gas.
    • Reperfusion washes out acid and potassium from the ischaemic leg.
    • Dark urine means myoglobin: fluids and bicarbonate to alkalinise the urine. After surgery
    • A tense calf after reperfusion means compartment syndrome and urgent fasciotomy.
    • Heparin resumes after surgery to stop the clot propagating.
  4. Crisis

    As flow returns, T waves become peaked and the QRS broadens; HR falls to 42, BP 84/50. What do you do?

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    • Bradycardia algorithm with a clear cause: hyperkalaemia on reperfusion, slow and hypotensive. (Crisis)
    • Treat the cause first: calcium chloride 500–1000 mg IV over 3 minutes.
    • Insulin 10 units with 50 g glucose IV.
    • Sodium bicarbonate for her acidosis, which also lowers potassium.
    • Still slow: atropine 1 mg every 3–5 minutes, up to 3 mg.
    • No response: adrenaline 2–10 mcg/min or transcutaneous pacing.
  5. Crisis

    Minutes later the ECG becomes a broad sine wave and she has no pulse. What do you do?

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    • Adult arrest algorithm: PEA with a sine wave from hyperkalaemia; CPR started now. Crisis
    • Non-shockable rhythm: give adrenaline 1 mg straight away, repeating every 3–5 minutes.
    • Insulin-glucose, with calcium and bicarbonate considered; benefit in arrest is uncertain.
    • Shock at once if it turns into VF.
    • Other causes for her: acidosis, bleeding into the wound, and hypoxia.
    • After return of circulation: ICU, repeated potassium and limb checks. After surgery

Fatal mistakes

  • Spinal or epidural on therapeutic heparin.
  • Missing hyperkalaemia on reperfusion.
  • Suxamethonium with a raised potassium.
  • Delaying revascularisation of the limb.

Checked against: Stoelting 8e · Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: ASRA Pain Medicine evidence-based guidelines (fifth edition) (2025) · AHA guidelines: special circumstances of resuscitation (2025) · Miller 10e · Faust

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