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Thoracic and vascular · Core03 / 11

Anterior mediastinal mass with SVC obstruction for node biopsy16-year-old boy, 58 kg, for urgent excision biopsy of a left supraclavicular node to diagnose a mass in the anterior mediastinum

Anterior mediastinal mass: keeping spontaneous breathing and rescue positions

From memory: the diagnosis and the notes are hidden. Answer each question aloud, then press Show.

Know this first

  • Children with over 50% tracheobronchial compression on CT cannot safely have general anaesthesia.
  • Supine breathlessness predicts airway obstruction; supine faintness suggests vascular compression.
  • Steroids before tissue may shrink the mass but can hide the diagnosis.
  • Rescue: change his position, or pass a rigid bronchoscope past the narrowing.

The patient

16-year-old boy, 58 kg, for urgent excision biopsy of a left supraclavicular node to diagnose a mass in the anterior mediastinum, probably lymphoma. Breathless lying flat and sleeps sitting up; swollen face and arms with distended neck veins. CT: trachea narrowed by 55% just above the carina; SVC compressed; small pericardial effusion. Vitals: BP 116/70, HR 112, SpO2 96% sitting and 91% lying flat, RR 26.

The examiner asks

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  1. Consider

    What are your concerns?

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    • A 16-year-old with a big anterior mediastinal tumour obstructing his SVC, for urgent node biopsy. Patient
    • As a teenager his airway is softer, and most anaesthetic deaths here have been in children.
    • He can't lie flat, so the mass may close his airway once he is asleep. Disease
    • His tracheal narrowing sits just above the carina, past where a tube reaches. Airway
    • His SVC is compressed and he has an effusion, so his circulation is at risk too. Disease
  2. Prepare

    How do you assess his risk?

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    • Symptoms graded: he cannot tolerate supine at all, which is the severe grade. Disease
    • CT shows 55% tracheal narrowing; over 50% in a child means general anaesthesia is unsafe. Airway
    • Echo for the effusion and any compression of the heart or pulmonary artery. Disease
    • Mild symptoms wouldn't reassure me; symptoms don't predict how bad collapse will be under anaesthesia.
    • I ask him which position eases his breathing, since that is my rescue position. Airway
  3. Prepare

    What do you discuss with the team before the biopsy?

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    • Tissue from outside the chest first: this neck node under local anaesthesia. Surgery
    • Steroids before biopsy may shrink the mass but can hide the diagnosis; oncology decides. Disease
    • Cannulas in his legs, because arm veins drain into the blocked SVC.
    • Arterial line, and only modest fluid; too much worsens SVC obstruction.
    • Rigid bronchoscope and surgeon in the room; ECMO team aware, not relied on for rescue. Airway
  4. Plan

    If he does need anaesthesia, how will you do it?

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    • Sitting up, local anaesthetic infiltration, and light dexmedetomidine so he keeps breathing. Airway
    • If deeper is needed, sevoflurane or titrated ketamine, keeping spontaneous breathing throughout.
    • No relaxant unless I've first proved I can ventilate him by hand.
    • Flat supine is never required for this; he stays in his best position.
    • He is watched closely in recovery; airway obstruction now often happens after surgery. After surgery
  5. Crisis

    Under sedation he is laid flat for draping. SpO2 falls to 82%, BP to 70/40, and he is struggling to breathe. What do you do?

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    • Sit him straight back up and stop the sedation; 100% oxygen. Crisis
    • Not better: turn him lateral or prone, to his position of relief.
    • Let him wake up fully if he isn't recovering; consciousness is protecting his airway.
    • Total obstruction: rigid bronchoscope past the mass to ventilate below it.
    • Phenylephrine 50–100 mcg through a leg cannula for his pressure while positioning works.
    • Once he is safe, the biopsy proceeds sitting under local, or stops for oncology to replan. After surgery

Fatal mistakes

  • A muscle relaxant before ventilation beyond the mass is proven.
  • Upper-limb cannulas only in SVC obstruction.
  • Supine general anaesthesia without a rescue position or rigid bronchoscope.
  • Relying on bypass standby to rescue sudden airway collapse.

Checked against: Miller 10e · Stoelting 8e

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