Anterior mediastinal mass with SVC obstruction for node biopsy16-year-old boy, 58 kg, for urgent excision biopsy of a left supraclavicular node to diagnose a mass in the anterior mediastinum
Anterior mediastinal mass: keeping spontaneous breathing and rescue positions
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Know this first
- Children with over 50% tracheobronchial compression on CT cannot safely have general anaesthesia.
- Supine breathlessness predicts airway obstruction; supine faintness suggests vascular compression.
- Steroids before tissue may shrink the mass but can hide the diagnosis.
- Rescue: change his position, or pass a rigid bronchoscope past the narrowing.
The patient
The examiner asks
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Consider
What are your concerns?
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- A 16-year-old with a big anterior mediastinal tumour obstructing his SVC, for urgent node biopsy. Patient
- As a teenager his airway is softer, and most anaesthetic deaths here have been in children.
- He can't lie flat, so the mass may close his airway once he is asleep. Disease
- His tracheal narrowing sits just above the carina, past where a tube reaches. Airway
- His SVC is compressed and he has an effusion, so his circulation is at risk too. Disease
Prepare
How do you assess his risk?
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- Symptoms graded: he cannot tolerate supine at all, which is the severe grade. Disease
- CT shows 55% tracheal narrowing; over 50% in a child means general anaesthesia is unsafe. Airway
- Echo for the effusion and any compression of the heart or pulmonary artery. Disease
- Mild symptoms wouldn't reassure me; symptoms don't predict how bad collapse will be under anaesthesia.
- I ask him which position eases his breathing, since that is my rescue position. Airway
Prepare
What do you discuss with the team before the biopsy?
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- Tissue from outside the chest first: this neck node under local anaesthesia. Surgery
- Steroids before biopsy may shrink the mass but can hide the diagnosis; oncology decides. Disease
- Cannulas in his legs, because arm veins drain into the blocked SVC.
- Arterial line, and only modest fluid; too much worsens SVC obstruction.
- Rigid bronchoscope and surgeon in the room; ECMO team aware, not relied on for rescue. Airway
Plan
If he does need anaesthesia, how will you do it?
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- Sitting up, local anaesthetic infiltration, and light dexmedetomidine so he keeps breathing. Airway
- If deeper is needed, sevoflurane or titrated ketamine, keeping spontaneous breathing throughout.
- No relaxant unless I've first proved I can ventilate him by hand.
- Flat supine is never required for this; he stays in his best position.
- He is watched closely in recovery; airway obstruction now often happens after surgery. After surgery
Crisis
Under sedation he is laid flat for draping. SpO2 falls to 82%, BP to 70/40, and he is struggling to breathe. What do you do?
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- Sit him straight back up and stop the sedation; 100% oxygen. Crisis
- Not better: turn him lateral or prone, to his position of relief.
- Let him wake up fully if he isn't recovering; consciousness is protecting his airway.
- Total obstruction: rigid bronchoscope past the mass to ventilate below it.
- Phenylephrine 50–100 mcg through a leg cannula for his pressure while positioning works.
- Once he is safe, the biopsy proceeds sitting under local, or stops for oncology to replan. After surgery
Fatal mistakes
- A muscle relaxant before ventilation beyond the mass is proven.
- Upper-limb cannulas only in SVC obstruction.
- Supine general anaesthesia without a rescue position or rigid bronchoscope.
- Relying on bypass standby to rescue sudden airway collapse.
Checked against: Miller 10e · Stoelting 8e
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