We do the sorting. You do the medicine.

Cardiac

Sheet 01Anaesthesia

Cardiac

Preoperative assessment, arrhythmia, ischaemia, valves, heart failure and the cardiomyopathies.

Cards
31
Minutes
about28
Scenarios
31

Start at card 1Review the rules

Core rulesRead these first3 cards · about 2 min

  1. 01The governing rule
  2. 02The algorithm, five steps
  3. 03Functional capacity: the number everything turns on

The governing rule

01 / 31

Order a preoperative test only when its result would change management; otherwise skip it.

Surgery

SurgeryPreoperative testing
Emergency or low‑risk surgery, open its explanationSkip the test, however sick

Effect of the test result

Effect of the test resultPreoperative testing
Management the same either way, open its explanationSkip the test
Result would change management, open its explanationOrder it: delay, other treatment, anaesthetic, monitoring or postoperative plan

Sources: AHA/ACC 2024 · §1.5

Report a problem with card 1: The governing rule

The algorithm, five steps

02 / 31

Five steps in order: stop at the first that applies; stress-test only at step 5.

1Is the surgery an emergency?

SurgeryWhat to do
Emergency: life or limb, typically under 2 hours, open its explanationStraight to theatre; older texts still say 6 hours
Emergency surgery despite recent infarct or heart failure, open its explanationStraight to theatre; no stress test or angiography first
Aneurysmal subarachnoid haemorrhage (SAH): ST depression, raised troponin, normal LV, open its explanationProceed to surgery; don't delay for ECG/troponin changes

2Is there an active cardiac condition?

Cardiac statusWhat to do
Active cardiac disease, open its explanationStop and refer

3Is the combined risk low (under 1% major adverse cardiac events (MACE))?

FindingVerdict
Low‑risk surgery, even with coronary disease, open its explanationNo testing; proceed
Capacity unassessable (joint pain), Revised Cardiac Risk Index (RCRI) 0, open its explanationNo further cardiac testing; never a stress test
Coronary disease plus diabetes, hypertension, older age, open its explanationCoronary disease carries most of the infarct and cardiac‑death risk

4Is functional capacity 4 metabolic equivalents (METs) or more?

CapacityWhat to do
Functional capacity 4 METs or more, open its explanationNo stress testing

5Poor or unknown capacity

CapacityWhat to do
Elevated risk, under 4 METs or unknown, open its explanationStress test, only if result changes management

Sources: AHA/ACC 2024 · §1.5AHA/ACC 2024 · §4.3AHA/ACC 2024 · §4.5AHA/ACC 2024 · §4.2.1

Report a problem with card 2: The algorithm, five steps

Functional capacity: the number everything turns on

03 / 31

Before major surgery, every capacity measure has a fixed cut-off; ask and test, never estimate.

Capacity measure

Capacity measureVerdict
Under 4 METsLow functional capacity
Duke Activity Status Index (DASI) ≤34Low functional capacity
Walks two blocks (3 METs)Fails: low functional capacity
Climbs one flight of stairs (5 METs)Passes: adequate functional capacity
Elevated risk, at least 4 METs without symptoms, open its explanationProceed; no echo, stress testing or cardiology referral

Biomarker in at-risk surgery

Biomarker in at-risk surgeryWhat to do
B‑type natriuretic peptide (BNP) ≤92Normal: stop the workup
NT‑proBNP <300 ng/LNormal: stop the workup

Activity

ActivityMETs
Gardening, open its explanation4 METs, the textbook activity
Walking, pace not stated, open its explanation4 METs; a slow stroll of a block or two is lower
Sustained fast swimming, open its explanation10 METs or more

Report a problem with card 3: Functional capacity: the number everything turns on

Part 1 · DecisionsWhat to do6 cards · about 7 min

  1. 04Proceed, postpone, or refer
  2. 05Which test
  3. 06Scoring the risk
  4. 07Which drug to stop, hold or continue
  5. 08How long to wait
  6. 09Procedures with their own rule

Proceed, postpone, or refer

04 / 31

Unstable heart conditions delay elective surgery; emergencies and stable patients proceed, with setting adjusted to risk.

FindingWhat to do
Right bundle branch block (RBBB) plus young sudden family death, open its explanationRefer to cardiology for inherited arrhythmia, e.g. Brugada; do not proceed
Good functional capacity or emergency, open its explanationProceed; no further work‑up
Rest angina before non‑emergency surgery, open its explanationRefer to cardiology; never proceed or stress test first
Diabetic hypertensive pre‑op: chest pain, dyspnoea, ST elevation, open its explanationPostpone surgery; urgent cardiology review, primary percutaneous coronary intervention (PCI)
Elevated risk, under 4 METs, cannot exercise, open its explanationPharmacological stress test; echo if unexplained dyspnoea
Hypotension, back pain, pulsatile mass, open its explanationRuptured abdominal aortic aneurysm (AAA): straight to theatre; permissive hypotension, no echo
Basal crackles with severe aortic regurgitation, open its explanationPostpone; treat and optimise heart failure first
Day‑case TURP (transurethral resection of the prostate) in severe heart failure, open its explanationStable: proceed and admit as an inpatient
Simultaneous bilateral knee replacement, open its explanationStage it for severe systemic disease, over 75, poor ventricle

Sources: AHA/ACC 2024 · §1.5AHA/ACC 2024 · §7.7

Report a problem with card 4: Proceed, postpone, or refer

Which test

05 / 31

Order each cardiac test or line only for its specific indication, never routinely.

Tests before and after surgery

FindingTest to order
Valve lesion, unexplained dyspnoea, worsening heart failure, open its explanationEchocardiogram; never routine, nor for stable cardiomyopathy
Known cardiac disease, elevated‑risk surgery, open its explanationECG; never for low‑risk surgery
Age alone, no other indication, open its explanationNo ECG for low‑risk surgery; European Society of Cardiology (ESC) counts age ≥65 otherwise
Unassessable capacity, risk factors only, RCRI 0, open its explanationNo stress test; BNP if a test is forced
Cardiac marker needed, open its explanationTroponin I or T, not troponin C
Postoperative: cardiovascular disease, risk factors, high‑risk surgery, open its explanationTroponin I or T surveillance against preoperative baseline; not BNP, lactate dehydrogenase (LDH), CK‑MB
Postoperative symptomatic ischaemia, open its explanationBedside treatment and troponin now; catheterisation last
Advanced chronic obstructive pulmonary disease (COPD) or suspected mass, open its explanationChest X‑ray, selectively; only for specific findings

Lines and catheters

DeviceWhen to place
Central venous line, open its explanationCentral venous pressure (CVP) monitoring, pulmonary artery catheter, pacing, dialysis, vasoactive drugs
Pulmonary artery catheter, open its explanationShock on inotropes; right failure, fluid shifts; refractory left failure

Sources: AHA/ACC 2024 · §4.3AHA/ACC 2024 · §4.2.1

Report a problem with card 5: Which test

Scoring the risk

06 / 31

Score each tool by its exact criteria: RCRI predicts cardiac complications, CHA2DS2-VASc predicts stroke.

Revised Cardiac Risk Index (RCRI) criteria (Lee 1999; Faust, Barash)

Criterion, 1 point eachCounts when
High‑risk surgery, open its explanationIntraperitoneal (laparoscopic too), intrathoracic or suprainguinal vascular
Ischaemic heart disease, open its explanationPrevious infarct, positive exercise test, ischaemic chest pain or nitrate use
Heart failure, open its explanationAny history of heart failure
Cerebrovascular disease, open its explanationAny previous stroke or transient ischaemic attack (TIA)
Diabetes, open its explanationOnly if treated with insulin; tablets score 0
Creatinine, open its explanationOnly above 2 mg/dL (176 µmol/L)
Age or hypertension, open its explanationZero points; neither is an RCRI criterion

RCRI score and risk of major cardiac complications (Lee 1999)

RCRI scoreComplication rate: derivation · validation
0, open its explanationDerivation 0.5%; validation 0.4%
1, open its explanationDerivation 1.3%; validation 0.9%
2, open its explanationDerivation 4%; validation 6.6%
3 or more, open its explanationDerivation 9.1%; validation 11%
Risk level (Faust), open its explanation0 very low · 1 low · 2 moderate · 3 or more high

Worked RCRI sums

CaseSum and risk
Stable angina, diabetes on tablets, open its explanation1 + 0 = 1 point: about 1% (validation 0.9%)
Colon resection, heart failure, insulin‑treated diabetes, open its explanation1 + 1 + 1 = 3 points: the 3‑or‑more class
Laparoscopic cholecystectomy, insulin, nitrate‑treated angina, creatinine under 2 mg/dL, open its explanation1 + 1 + 1 + 0 = 3 points: high risk

CHA2DS2-VASc stroke score in atrial fibrillation (Stoelting)

CriterionPoints
Congestive heart failure, open its explanation1
Hypertension, open its explanation1
Age 75 or over, open its explanation2
Diabetes, open its explanation1
Previous stroke or TIA, open its explanation2
Vascular disease, open its explanation1
Age 65 to 74, open its explanation1
Female sex, open its explanation1

CHA2DS2-VASc score, stroke risk and anticoagulation (Miller; 2019 ACC/AHA)

ScoreMeaning
Patients scored (also by the older congestive heart failure, hypertension, age, diabetes, stroke (CHADS2) score), open its explanationNonvalvular atrial fibrillation only; not rheumatic mitral stenosis or prosthetic valve
0, open its explanationLow: stroke 0.2% a year
1, open its explanationIntermediate: stroke 0.6% a year
2 or more, open its explanationHigh: stroke over 2.2% a year
Men 0, women 1, open its explanationLong‑term anticoagulation may be omitted
Men 1, women 2, open its explanationAnticoagulation may be considered
Men 2 or more, women 3 or more, open its explanationLong‑term oral anticoagulation recommended

Report a problem with card 6: Scoring the risk

Which drug to stop, hold or continue

07 / 31

Continue cardioprotective drugs; hold those risking hypotension, hypoglycaemia or bleeding.

Cardiac and diabetes medicines

DrugBefore surgery
Chronic beta blocker or statin, open its explanationContinue perioperatively
New beta blocker, open its explanationStart at least 1 week before, slowly titrated
Beta blocker contraindication, open its explanationDecompensated failure, severe bronchospasm, high‑grade block, bradycardia
Angiotensin‑converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB), major fluid shifts, open its explanationHold 24 hours pre‑op; individualise, not routine stopping
Induction hypotension on a continued ACE inhibitor or ARB, open its explanationExpected; omitting it 24 hours before improves stability
Metformin or sulfonylurea, open its explanationHold on the morning of surgery
Sodium‑glucose cotransporter 2 (SGLT2) inhibitor, open its explanationStop 3–4 days before; euglycaemic ketoacidosis risk

Anticoagulant name endings (official drug-naming lists, outside the books)

Name endingClass
-parin (enoxaparin, dalteparin), open its explanationHeparin: acts through antithrombin
-xaban (rivaroxaban, apixaban, edoxaban), open its explanationDirect factor Xa inhibitor
-gatran (dabigatran), open its explanationDirect thrombin inhibitor
-irudin (bivalirudin, lepirudin), open its explanationDirect thrombin inhibitor, hirudin type
Warfarin, open its explanationVitamin K antagonist; no class ending

Stop times before high-bleeding-risk surgery

AgentStop before surgery
Factor Xa inhibitor≥3 days
Dabigatran≥4 days; 5–6 if creatinine clearance (CrCl)<50
Clopidogrel5 days
Ticagrelor3 days
Prasugrel7 days
Ticlopidine10 days
Rivaroxaban at 24 hoursLow‑bleeding‑risk surgery only, not neuraxial

Sources: AHA/ACC 2024 · §6.3

Report a problem with card 7: Which drug to stop, hold or continue

How long to wait

08 / 31

Delay elective surgery according to stent age and indication; urgent surgery goes ahead without waiting.

Elective surgery after a coronary stent or infarct

Stent and settingWhen to operate
Any coronary stent, within 30 days of PCI, open its explanationNever operate electively
Stent placed for acute coronary syndrome (ACS), open its explanationWait 12 months before elective surgery
Drug‑eluting stent, chronic coronary disease, open its explanationWait 6 months, not 12
Myocardial infarction (MI) with catheterisation: assume a stent, open its explanationPostpone 6 months; 60 days if no stent
Drug‑eluting stent, clopidogrel stopped early, elective surgery, open its explanationCancel, restart clopidogrel, rebook 6 months from placement
Time‑sensitive surgery after stent, open its explanationCan proceed at 3 months
Urgent surgery after stent, open its explanationProceed now on continued aspirin or dual antiplatelet therapy (DAPT)

Hip fracture timing

Hip fractureWhen to operate
Any hip fracture, open its explanationWithin 48 hours; delay raises mortality
Bare‑metal stent placed 6 weeks ago, open its explanationOperate now rather than wait further

Drug-eluting stent over a year

Drug-eluting stent over a yearAntiplatelet plan
Drug‑eluting stent over one year, arthroplasty, open its explanationContinue aspirin through arthroplasty
Second antiplatelet, drug‑eluting stent over one year, open its explanationStop, timed by its pharmacology and renal function

Sources: AHA/ACC 2024 · §7.5

Report a problem with card 8: How long to wait

Procedures with their own rule

09 / 31

Each procedure here follows its own condition-specific rule, not the general default.

SituationWhat to do
Mitral stenosis in labour, open its explanationVaginal delivery, early neuraxial analgesia, never withheld
High‑risk cardiac lesion, gingival dental work, open its explanationProphylaxis; not for gastrointestinal or genitourinary procedures
Dental work: which hearts get prophylaxis, open its explanationAny prosthetic valve or repair material; unrepaired cyanotic congenital disease
Child, unrepaired cyanotic heart disease, no allergy, open its explanationIV cefazolin 50 mg/kg, max 1 g; skip clindamycin
Postoperative epidural in cardiac diseaseContinue thoracic epidural at least 24 hours, optimally 2–4 days
Lithotripsy: pregnancy, bleeding disorder, anticoagulationAbsolute; pacemaker, implantable cardioverter‑defibrillator (ICD), aneurysm, obesity only relative
Aortic stenosis or murmur found before elective surgery, open its explanationTransthoracic Doppler echo: grades severity and ventricular function
Severe aortic stenosis, pregnant, requesting epidural, open its explanationCatheter epidural, extend slowly; relative contraindication only
Coronary disease before non‑cardiac surgery, open its explanationRevascularise only where indicated anyway: ST‑elevation myocardial infarction (STEMI), high‑risk non‑ST‑elevation myocardial infarction (NSTEMI), left main

Sources: AHA/ACC 2024 · §6.1.1AHA/ACC 2024 · §4.3

Report a problem with card 9: Procedures with their own rule

Part 2 · RecognitionWhat it is5 cards · about 5 min

  1. 10The ECG
  2. 11Waveforms and pressures
  3. 12Echo
  4. 13Murmurs, grades and numbers
  5. 14The action potential

The ECG

10 / 31

Each ECG pattern points to one specific diagnosis, lead or artery, not its look-alike.

QT and electrolytes

FindingWhat it is
Severe hypokalaemia with U waves, open its explanationProlonged QT(U), not third‑degree block
Electrolyte cause of a prolonged QT, open its explanationHypocalcaemia (also low magnesium or potassium); never high potassium
Torsades with hypotension during surgery, open its explanationMagnesium deficiency, long QT; 1–2 g IV magnesium

Bundle branch blocks

FindingWhat it is
QRS over 120 ms, notched lateral R, open its explanationComplete left bundle branch block (LBBB)
LBBB: lateral leads I, aVL, V5, V6, open its explanationBroad notched R, no septal Q; V1 mainly negative
rSR′ in V1, open its explanationRBBB, not LBBB

Diagnostic patterns

FindingWhat it is
Epsilon wave, V1–V3, open its explanationArrhythmogenic right ventricular cardiomyopathy; minor Padua criterion
Arrest with coved right precordial ST elevation, open its explanationBrugada syndrome: pseudo‑RBBB, sodium‑channel disorder, normal heart
Diffuse ST elevation, PR depression, open its explanationAcute pericarditis, not territorial infarct
Low QRS voltage ± alternansPericardial effusion, COPD, constrictive pericarditis, restrictive cardiomyopathy

Ischaemia monitoring leads

Lead or leadsWhat it means
Most sensitive two‑lead ischaemia pair, open its explanationV4 with V5; the usual II with V5 is less sensitive
V5, open its explanationBest single ischaemia lead
Five‑lead versus three‑lead ECG, coronary disease, open its explanationFive leads detect more ST‑segment changes; V5 needs five electrodes
II, V4 and V5, open its explanationHighest ischaemia sensitivity

Electrodes and territories

Lead or territoryWhat it means
Leads II and IIILeft‑leg positive electrode; lead I unaffected
Lateral territory, open its explanationCircumflex artery

Report a problem with card 10: The ECG

Waveforms and pressures

11 / 31

Every waveform or pressure reading maps to one specific lesion, event or limit.

Arterial pulse

Arterial traceCause
Pulsus alternans, open its explanationFailing left ventricle
Single‑beat arterial dip; P persists, QRS absent, open its explanationSecond‑degree atrioventricular (AV) heart block; that beat not conducted
Pulsus bisferiens, open its explanationAortic regurgitation
Pulsus parvus et tardus, open its explanationAortic stenosis
Pulsus paradoxus, open its explanationTamponade or severe asthma
Spike‑and‑dome, open its explanationHypertrophic obstructive cardiomyopathy, not bisferiens

CVP wave

CVP waveMeaning
Raised CVP, blunted y, dominant x after chest stab, open its explanationCardiac tamponade
v wave, open its explanationLate systole: right atrium fills against the closed tricuspid valve
Absent a, augmented c, open its explanationAtrial fibrillation, even in mitral stenosis

End-tidal to arterial CO2 gradient

FindingMeaning
Widened gradient >5 mmHg, open its explanationDead space: pulmonary embolism, low output, overdistension
Restored or high cardiac output, open its explanationNarrows the gradient; embolism and overdistension widen it

Pulmonary artery catheter and wedge pressure

ReadingMeaning
Diastolic step‑up as the catheter advances, open its explanationTip has left the right ventricle (RV) for the pulmonary artery (PA)
RV end‑diastolic pressure, open its explanationEquals right atrial (RA) end‑diastolic pressure
Wedge pressure reads below left ventricular end‑diastolic pressure, open its explanationAortic regurgitation underestimates; also a stiff left ventricle
Wedge pressure above left ventricular end‑diastolic pressure (LVEDP), open its explanationPositive end‑expiratory pressure (PEEP) overestimates; mitral disease, atrial myxoma, non‑zone III catheter tip
Arteriovenous O2 difference outside 3–5 mL/dL, open its explanationAbnormal

Pressure–volume loop

Point on the loopEvent
Point D (pressure–volume loop or cycle graph), open its explanationMitral valve opens: rapid ventricular filling starts
Point C, open its explanationAortic valve closes at end‑systole; isovolumic relaxation begins

Pulse contour cardiac output

ConditionPulse contour output
Clean waveform with a dicrotic notch, open its explanationNeeded for a valid reading
Damping, arrhythmia, aortic regurgitation, intra‑aortic balloon pump (IABP), shifting systemic vascular resistance (SVR), open its explanationPulse contour output unreliable
Aortic stenosis alone, open its explanationStill reliable

Report a problem with card 11: Waveforms and pressures

Echo

12 / 31

Choose the echo view, cardiac timing or monitor that directly shows the problem.

Best transoesophageal view or monitor for the task

TaskWhat shows it best
Ischaemia monitoring on transoesophageal echocardiography (TOE), open its explanationTransgastric mid‑papillary short axis: all three coronary territories
Suspected massive pulmonary embolism, right ventricular strain, open its explanationFour‑chamber view: RV:LV ratio, D‑shaped septum, McConnell's sign
Femoral VV‑ECMO cannulation, open its explanationMid‑oesophageal bicaval: wire tracked along the cavae into RA
Suspected venous air embolism, open its explanationMid‑oesophageal bicaval view: right atrium, both venae cavae
Detecting venous air embolism, open its explanationTOE or precordial Doppler, not an oesophageal stethoscope

Structures on the TOE views

StructureWhat it is
Lateral wall, transgastric mid‑papillary short axis, open its explanationCircumflex; anterior is left anterior descending, inferior right coronary
Inferior vena cava (IVC) on bicaval viewNot the coronary sinus

Echo findings

FindingWhat it is
Dilated RV, D‑shaped septum, McConnell's sign, open its explanationMassive pulmonary embolism with RV strain
Early‑diastolic RV free wall collapse, open its explanationTamponade, not simple effusion
Systolic right atrial collapse, open its explanationSensitive, not specific; RV diastolic collapse confirms
Bubbles in the right atrium, bicaval view, open its explanationVenous air embolism; TOE is the most sensitive monitor

TOE contraindications

Finding before TOEContraindication
Oesophageal perforation, open its explanationAbsolute, the most serious; outranks old surgery
Previous oesophageal surgery, open its explanationRelative only: healed past disease, not a current breach

Report a problem with card 12: Echo

Murmurs, grades and numbers

13 / 31

Name each finding by its exact numbers or signs, not the look-alike.

Valve and ventricle thresholds

ThresholdWhat it means
Mitral area 1–1.5 cm², gradient 5–10 mmHg, open its explanationModerate mitral stenosis; severe under 1.0 cm²
Aortic <1 cm², >40 mmHg, >4 m/s, open its explanationSevere aortic stenosis; either area or gradient suffices
Ejection fraction (EF) <25%, pulmonary capillary wedge pressure (PCWP) >20 mmHg, cardiac index (CI) <2.5 L/min/m², open its explanationPoor dilated cardiomyopathy prognosis
EF ≤40%, open its explanationReduced ejection fraction
EF ≥50%, open its explanationPreserved ejection fraction

Signs and what they mean

FindingWhat it means
Apical holosystolic murmur, inferior MI, open its explanationPapillary muscle rupture, acute mitral regurgitation
Parasternal thrill with shockSeptal rupture
Sail‑like displaced tricuspid valve, open its explanationEbstein anomaly
Positional pain, fever, rub, open its explanationPericarditis, not pulmonary embolism (PE) or MI
Crackles, S3, dilatation, low EF, open its explanationReduced‑fraction heart failure, not hypertrophic cardiomyopathy
Raised CVP, hypotension, pulmonary hypertension in dilated cardiomyopathy, open its explanationPoor prognosis; systemic hypertension is not a marker

What to do

SituationWhat to do
Severe aortic stenosis, anaesthesia, open its explanationKeep preload, SVR, sinus rhythm, normal‑low rate
Ebstein anomaly, open its explanationDe‑air every intravenous line
Rheumatoid neck, deficits or limited movementImage C1–C2 first

Report a problem with card 13: Murmurs, grades and numbers

The action potential

14 / 31

Each cardiac myocyte action potential phase is defined by its dominant ion current.

PhaseDominant current
Phase 0 upstroke, open its explanationFast sodium influx through voltage‑gated sodium channels
Phase 1 notch, open its explanationTransient outward potassium current
Phase 2 plateau, open its explanationL‑type calcium influx balanced by potassium efflux
Phase 3 repolarisation, open its explanationDelayed rectifier potassium efflux
Phase 4 rest, open its explanationInward rectifier potassium current holding the resting potential

Report a problem with card 14: The action potential

Part 3 · SituationsWhat now6 cards · about 5 min

  1. 15On bypass
  2. 16Cross clamping and the aorta
  3. 17Rhythm in theatre
  4. 18Sudden haemodynamic deterioration
  5. 19Position and insufflation
  6. 20Complications of what you did

On bypass

15 / 31

Each bypass event has one specific move; the tempting alternative fails.

EventWhat to do
Heparin reversal, open its explanationProtamine, 1 mg/100 units heparin, test dose; not fresh frozen plasma (FFP)
Right ventricle distends, pressure collapses, open its explanationReheparinise, resume bypass; not balloon pump
Air in aortic line, open its explanationStop bypass immediately, not anti‑Trendelenburg or more flow
Pressure crash as bypass begins, open its explanationHaemodilution, falling resistance; not anaphylaxis or heparin‑induced thrombocytopenia
IABP timing, open its explanationInflate in diastole, deflate before systole; LV volume falls
Post‑CABG low index, high SVR, unraised wedge, open its explanationUnderfilled ventricle: give volume first, then reassess
Profound hypotension post‑bypass, chronic ARB/ACE inhibitor, open its explanationVasoplegia: vasopressor infusion; if refractory, vasopressin or methylene blue
Painless visual loss after bypass, open its explanationEmbolic branch retinal artery occlusion, not raised intraocular pressure
Isoelectric EEG on bypass, open its explanationHypothermia; cortex silent at about 18–20 °C
Circulatory arrest planned, open its explanationCool to 18 °C, not barbiturate or propofol
Flat EEG, milder cooling, open its explanationDrug intoxication, high volatiles, or brain death

Report a problem with card 15: On bypass

Cross clamping and the aorta

16 / 31

Treat each aortic clamping phase and aneurysm setting separately; timing decides which therapy belongs.

Clamp event

Clamp eventWhat to do
Proximal hypertension and falling cardiac output on clamping, open its explanationEsmolol or vasodilators
ST depression after aortic cross‑clamp, aneurysm repair, open its explanationIncreased myocardial oxygen consumption from raised afterload above clamp
Wedge pressure on cross‑clamping, open its explanationRises, with afterload and filling pressures
Open descending thoracic aortic repair: spinal cord protection, open its explanationCerebrospinal fluid (CSF) drainage plus distal (atriofemoral) bypass; keep proximal pressure up
Hypotension on unclamping, open its explanationReclamp or digital pressure; fluid‑load before release; pressors often needed

Aneurysm setting

Aneurysm settingMedical therapy
Aortic dissection, not aneurysm, before theatre, open its explanationPre‑emptive anti‑impulse therapy: lower contractility and pressure
Expanding aneurysm, theatre planned today, open its explanationNo new drug; continue any beta‑blocker, then proceed
Ruptured abdominal aortic aneurysm: most serious complication, open its explanationDeath ~50% perioperatively; renal failure common, spinal cord injury rare

Sources: AHA/ACC 2024 · §7.7

Report a problem with card 16: Cross clamping and the aorta

Rhythm in theatre

17 / 31

Let perfusion decide: unstable rhythms get shock or pacing, stable rhythms get drugs.

Tachycardias

RhythmWhat to do
Unstable atrial fibrillation (AF), including Wolff‑Parkinson‑White (WPW), open its explanationSynchronised cardioversion, not a drug
Stable new AF, open its explanationRate control
Stable thyrotoxic AF, open its explanationRate control with a beta blocker such as propranolol
Postoperative sinus tachycardia: sepsis or hypovolaemia, open its explanationTreat cause: restore volume, treat infection; no rate‑slowing drugs, cardioversion
Unstable wide‑complex tachycardia, open its explanationPulse check; synchronised cardioversion if pulse, defibrillate if pulseless
Stable supraventricular tachycardia (SVT) unresponsive to 6 mg adenosine, open its explanation12 mg rapid push; start at 3 mg via central line
Unstable SVT in a child, open its explanationSynchronised cardioversion 0.5–1 J/kg; 2 J/kg if that fails
Ventricular fibrillation during synchronised cardioversion, open its explanationUnsynchronised defibrillation immediately

Cardiac arrest

EventWhat to do
Ventricular fibrillation, open its explanationDefibrillate first, not amiodarone or adrenaline
End‑tidal carbon dioxide (PETCO2) not above 10 mmHg or falling, open its explanationReassess CPR quality
Two rescuers, before pulse checkCall emergency medical services (EMS), get defibrillator
Arrest leadershipOne leader who listens

Bradycardia and heart block

EventWhat to do
Flattening arterial trace with dropped QRS, open its explanationHeart block, not disconnected transducer
Heart block awaiting transvenous pacing, open its explanationTranscutaneous pacing or isoprenaline, dopamine, adrenaline; atropine rarely works

Report a problem with card 17: Rhythm in theatre

Sudden haemodynamic deterioration

18 / 31

Name the true cause of deterioration before treating; the reflex response often harms.

Hypotension and shock: the right drug

EventWhat to do
Hypotension in mitral stenosis, aortic stenosis, hypertrophic obstructive cardiomyopathy (HOCM), open its explanationPhenylephrine, plus fluid in HOCM; never ephedrine, adrenaline, atropine
Hypotensive cardiogenic shock, first vasopressor, open its explanationNoradrenaline, not dopamine or adrenaline
Poor perfusion once pressure is restored, open its explanationAdd an inotrope or a balloon pump
Dobutamine in cardiogenic shock, open its explanationOnly without hypotension or hypoperfusion; else noradrenaline
Local anaesthetic toxicity dysrhythmias: give, open its explanationLipid, adrenaline under 1 mcg/kg, amiodarone; bypass if refractory
Local anaesthetic toxicity dysrhythmias: avoid, open its explanationVasopressin, calcium‑channel or beta blockers, more local anaesthetic
Tamponade at induction: do, open its explanationFill first, keep rate high‑normal; drain under local if unstable
Tamponade at induction: avoid, open its explanationPositive pressure, vasodilators, myocardial depressants, bradycardia
Hypertension after carotid endarterectomy, open its explanationCarotid sinus denervation: the baroreceptor brake is lost
Hypotension with fast pulse, hours after carotid endarterectomy, open its explanationBleeding until proven otherwise; a slow pulse means the reflex

Contrast reaction timing

Contrast reactionOnset
Pruritus, urticaria, angioedema, rhinitis, bronchospasm, laryngeal oedemaImmediate

Report a problem with card 18: Sudden haemodynamic deterioration

Position and insufflation

19 / 31

Surgical positioning and insufflation bring predictable physiological changes; anticipate their direction and timing.

Thoracic kyphoscoliosis surgery

Thoracic kyphoscoliosis surgeryWhat to plan for
Kyphoscoliosis with mitral valve prolapseReduced lung volumes; possible right ventricular dysfunction
Major spinal correction, even with mitral prolapse, open its explanationBleeding and hypothermia, not the prolapse: replace volume, conserve blood

Head-down tilt

Head-down tiltHaemodynamic effect
Heart failure with mitral regurgitation, robotic surgery, open its explanationCompensated: minimal stepwise tilt; decompensated: open or extraperitoneal

Report a problem with card 19: Position and insufflation

Complications of what you did

20 / 31

Trace each complication to its cause (device, gas, position or drug) and act on that.

Pulmonary artery catheter injury

FindingWhat it is
Valve leaflet trauma from a PA catheter, open its explanationAt insertion or later from a dwelling catheter; not arterial lines

Cocaine and amphetamines

FindingWhat it is
Cocaine or amphetamine: stroke, arrhythmia, ischaemia, seizures, open its explanationInhibited neurotransmitter uptake, not increased reuptake
Cocaine or amphetamine, intraoperative period, open its explanationExpect hypertension, not hypotension

Report a problem with card 20: Complications of what you did

Part 4 · Conditions and mechanismsWhy it is true10 cards · about 8 min

  1. 21Implanted devices
  2. 22The cardiomyopathies and muscle disease
  3. 23The reflexes, as a set
  4. 24Physiology worth holding
  5. 25Drugs
  6. 26Anatomy that decides a line
  7. 27Monitoring and safety
  8. 28Congenital heart disease in children
  9. 29Heart disease in pregnancy
  10. 30Heart failure

Implanted devices

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Cautery risk depends on current path and device type; set the mode deliberately, then interrogate.

Pacemakers and cautery: what to do

SituationWhat to do
Symptomatic bradycardia, open its explanationPermanent pacemaker if symptoms are proven rate‑related; else weaker indication
Monopolar cautery above umbilicus, pacemaker‑dependent, open its explanationReprogram to asynchronous pacing; magnet only if reprogramming unavailable
Rapid sequence induction, pacing‑dependent ICD, no interrogation possible, open its explanationAvoid suxamethonium: fasciculations inhibit pacing, trigger shocks; use non‑depolarising relaxant
Cautery near a pacemaker, open its explanationBipolar cautery, short bursts, return pad away from generator
Sick sinus syndrome, pacemaker, knee replacement, diathermy planned, open its explanationAvoid diathermy if possible; else bipolar, short bursts
Pacemaker after cautery, open its explanationInterrogate the device

Device behaviour

Device featureWhat it does
Magnet over an ICD, open its explanationSuspends antitachycardia therapy only, not asynchronous pacing
Third pacemaker code letter, open its explanationResponse to sensing: inhibit, trigger, dual
Subcutaneous defibrillatorNever paces
Hyperkalaemia with a pacemaker, open its explanationCan cause failure to capture

Inappropriate shock risk

FactorShock risk
Cautery misread as shockable rhythm, open its explanationCan trigger an inappropriate shock
Suxamethonium at rapid sequence induction, open its explanationFasciculations can trigger a shock; rocuronium does not
Monopolar cautery, current across the generator, unipolar leads, open its explanationRaise inappropriate shock risk
Bipolar leads, or bipolar cautery below the umbilicus, open its explanationSafe

Sources: AHA/ACC 2024 · §6.6

Report a problem with card 21: Implanted devices

The cardiomyopathies and muscle disease

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Behind each misleading surface picture lies the cardiomyopathy itself; name it and treat it accordingly.

Cardiomyopathy findings

FindingWhat it is
Apparently stable HOCM at baseline, open its explanationMisleading; obstruction still hidden
HOCM with tachycardia, hypovolaemia or falling afterload, open its explanationUnmasked outflow obstruction
Becker muscular dystrophy, open its explanationCardiac abnormality in 50–70%, not proportional to weakness
Heart failure and dysrhythmias in phaeochromocytoma, open its explanationCatecholamine‑induced cardiomyopathy
Hypertension in phaeochromocytoma, open its explanationUsually sustained; paroxysms only occasional but dangerous
New breathlessness in dilated cardiomyopathy, open its explanationPulmonary oedema, not effusion, atelectasis or embolism
Hypotension with tachycardia in dilated cardiomyopathy, open its explanationLow output from decompensated heart failure

Cardiomyopathy management

SituationWhat to do
Negative inotropes in HOCM, open its explanationKeep them running
Drug to raise cardiac output in HOCM, open its explanationBeta‑blocker such as propranolol; dopamine, nitrates and nitroprusside reduce output
Perioperative hypotension in HOCM, open its explanationFluid plus an alpha agonist; never adrenaline
Anaesthesia in Becker muscular dystrophy, open its explanationCardiology review however mild; trigger‑free: rhabdomyolysis, Stoelting says malignant hyperthermia (MH)

Sources: AHA/ACC 2024 · §6.3.1

Report a problem with card 22: The cardiomyopathies and muscle disease

The reflexes, as a set

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Intraoperative bradycardia is never reassuring: it is either a vagal reflex or extreme blood loss.

Reflex bradycardia from surgical handling

EventWhat to do
Bradycardia, hypotension on eye‑muscle traction, open its explanationOculocardiac reflex: surgeon stops traction first
High PaCO2, hypoxaemia or light anaesthesia, eye surgery, open its explanationStronger oculocardiac reflex: ventilate, oxygenate, deepen anaesthesia
Bradycardia, hypotension on carotid manipulation, open its explanationCarotid baroreceptor reflex: surgeon stops first
Bradycardia, hypotension during microvascular decompression, open its explanationVagal reflex: surgeon stops first

Other bradycardia reflexes

FindingWhat it is
Bradycardia in massive haemorrhage, open its explanationExtreme blood loss, not reassurance
Bradycardia, hypotension, coronary dilatation from the left ventricle, open its explanationBezold–Jarisch reflex: ischaemic or underfilled ventricle; never tachycardia
Chest pain, ST changes, bradycardia despite hypotension, open its explanationBezold–Jarisch reflex from the ischaemic left ventricle
Pelvic bleed, bradycardia, carotid/aortic receptors firing, open its explanationChemoreceptor reflex (acidosis, hypoxia): more breathing, slower heart, less contractility

Report a problem with card 23: The reflexes, as a set

Physiology worth holding

24 / 31

Predict the cardiovascular response first; it dictates what to expect and what to give.

Coronary perfusion

FindingWhat to expect
Rising heart rateLeft ventricular flow falls, not right ventricular
Coronary perfusion timing, right versus left ventricle, open its explanationRight ventricle systole and diastole; left ventricle diastole only

The denervated transplanted heart

Drug or eventWhat to expect or give
Transplanted heart bradycardia or hypotension, open its explanationAdrenaline or isoprenaline, not atropine or ephedrine
Hydralazine or nimodipine, transplanted heart, open its explanationHypotension without reflex tachycardia; no baroreflex through denervated heart
Neostigmine reversal, transplanted heart, open its explanationGlycopyrrolate first; direct chronotrope drawn up
Digoxin, transplanted heart, open its explanationNo heart rate effect; slowing is vagal, absent when denervated

Cirrhosis

FindingWhat to expect or give
Cirrhosis circulation, open its explanationHigh output, low resistance, low haemoglobin, mixed venous ~90%
Cirrhosis hypotension, open its explanationAlpha agonist, not milrinone

Cardiac output and its nerves

FindingWhat it means
Intrinsic cardiac output determinants, open its explanationHeart rate and contractility; not preload or resistance
High spinal block, T1–T4, open its explanationBradycardia from unopposed vagal tone
Heart rate rises as the right atrium stretches, open its explanationBainbridge reflex
Cardiac innervation: sympathetic spinal levels, vagal receptor, open its explanationSympathetic from T1–T4; vagal acetylcholine acts on M2 receptors

Other responses

EventWhat to expect
Electroconvulsive therapy (ECT), open its explanationBradycardia/hypotension, then tachycardia/hypertension; cardiovascular effects dominate
Valsalva manoeuvre, open its explanationCentral venous pressure up; venous return, output, pressure down
Atrial natriuretic peptideVasodilates, natriuresis, raises glomerular filtration rate (GFR); inhibits renin and aldosterone
After hip or knee arthroplasty, open its explanationCardiac events first, then PE, pneumonia, infection
After hip fracture, open its explanationDelirium commonest; chest infection and heart failure also

Report a problem with card 24: Physiology worth holding

Drugs

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Name each drug's class and effect; in long QT, avoid QT-prolonging antiemetics and repeated classes.

Antiarrhythmic classes (Vaughan Williams; Lei et al. 2018, outside the books)

ClassBlocks · drugs
Class ISodium channels · Ia quinidine, Ib lidocaine, Ic flecainide
Class IIBeta receptors · esmolol, metoprolol, propranolol
Class IIIPotassium channels, longer QT · amiodarone, sotalol
Class IVNodal calcium channels · verapamil, diltiazem
AmiodaroneClass III; also class I, II and IV actions
Basis of the classesThe channel or receptor each drug blocks

Congenital long QT syndrome

FindingWhat it is
Congenital long QT syndrome, open its explanationInherited ion‑channel defect: longer action potential; torsades, sudden death

Nausea with a long QT

EventWhat to do
Long QT with nausea in recovery, open its explanationMetoclopramide over ondansetron or droperidol; keep ECG monitoring
Dexamethasone and granisetron already given as prophylaxis, open its explanationDo not repeat a class used for prophylaxis
Droperidol or ondansetron as rescue in long QT, open its explanationAvoid, both prolong QT

Beta-2 agonists

FindingDrug
Most potent beta‑2 agonist, falling SVR with tachycardiaIsoprenaline, not adrenaline, dobutamine or noradrenaline

Coronary vessel effects

AgentEffect on coronary vessels
Adenosine on coronary vessels, open its explanationDilator
Acetylcholine on coronary vessels, open its explanationDilates via intact endothelium; constricts muscle directly or when diseased
Histamine on coronary vessels, open its explanationMixed: H1 constricts, H2 dilates
Hyperoxia on coronary vessels, open its explanationCoronary blood flow falls

Report a problem with card 25: Drugs

Monitoring and safety

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Each value's meaning depends on its band, sampling site or anatomy, not magnitude alone.

Current at 60 Hz for one second

Current at 60 Hz for one secondEffect
100 to 300 mA, open its explanationVentricular fibrillation
6 A, open its explanationSustained contraction then normal rhythm; more is not simply worse
100 µA direct to the heart, open its explanationVentricular fibrillation

Mixed venous oxygen saturation

SampleWhat to know
Mixed venous oxygen saturation, open its explanationNormally about 75%, sampled in the pulmonary artery
Superior vena cava central line sample, open its explanationCentral, not mixed venous; reads higher in critical illness

Oesophageal Doppler

SituationWhat to know
Oesophageal Doppler monitor, open its explanationContinuous cardiac output from descending aortic Doppler shift
Oesophageal Doppler with aortic pathology, open its explanationUnreliable: aortic stenosis, regurgitation, thoracic aortic disease

Report a problem with card 27: Monitoring and safety

Congenital heart disease in children

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Know each lesion's shunt: protect preload and systemic resistance in tetralogy, spontaneous breathing in Fontan.

Induction in congenital heart disease

FactorWhat to do
Prolonged fasting, hypovolaemic hypotension, open its explanationAvoid both: keep preload and systemic resistance
Ketamine, open its explanationAcceptable; no need to avoid it

Tetralogy of Fallot spells

EventWhat to do
Tet spell, open its explanationEscalate: vasoconstrictor to raise SVR, then short‑acting β‑blocker or sedative
Dopamine during tet spell, open its explanationNever give it

Shunts and inhalational induction speed

ShuntInduction speed
Atrial septal defect with shunting from left to right, open its explanationNo effect; intravenous speed also unchanged
Tetralogy of Fallot with shunting from right to left, open its explanationSlower inhalational induction: less volatile reaches the brain

Recognising the lesion in infants

FindingLesion
Pink child sweats feeding, breathes fast, murmur, open its explanationSuspect ventricular septal defect: heart failure from a left‑to‑right shunt, not cyanotic
Infant sweats, desaturates feeding; saturation step‑up right atrium, open its explanationAtrial septal defect: saturation rise at right atrium localises shunt

Fontan circulation

SituationWhat to do
Fontan circulation under general anaesthesia, open its explanationSpontaneous breathing preferred; if ventilated, low pressures, keep preload

Report a problem with card 28: Congenital heart disease in children

Heart disease in pregnancy

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In pregnancy, fixed-output lesions carry highest maternal mortality; regurgitant lesions are well tolerated.

LesionIn pregnancy
Moderate‑severe mitral stenosis, open its explanationHighest maternal mortality among valve lesions
Severe aortic stenosis, open its explanationSevere threat if symptomatic; mitral stenosis ranks worse
Pulmonary hypertension, open its explanationHighest maternal mortality
Pulmonary hypertension in labour: main anaesthetic goal, open its explanationAvoid hypoxaemia, hypercarbia and acidosis, which raise pulmonary vascular resistance
Cyanotic heart disease, open its explanationHigh risk; deadliest when pulmonary hypertension (Eisenmenger)
Mitral or aortic regurgitation, open its explanationWell tolerated, unlike stenosis

Report a problem with card 29: Heart disease in pregnancy

Heart failure

30 / 31

End-stage heart failure that cannot proceed to transplant gets a destination left ventricular assist device (LVAD), not medical therapy alone.

TrapsCheck these before you finish1 card · about 1 min

  1. 31Traps

Traps

31 / 31

In preoperative cardiac assessment, apply each criterion exactly as defined; shortcuts and assumptions mislead.

Clinical situation

Clinical situationWhat to do
Rest angina, open its explanationRefer, not test
Emergency surgery or good functional capacity, open its explanationEnd the algorithm, whatever the risk factors
Normal ECG, open its explanationExcludes nothing; not reassurance

Risk calculation element

Risk calculation elementCheck before scoring
Diabetes, open its explanationScores only if on insulin
CreatinineConfirm the units before applying the threshold
TroponinConfirm which isoform was measured

Sources: AHA/ACC 2024 · §1.5

Report a problem with card 31: Traps

QuizCheck yourself31 practice scenarios · one to a screen

QuizCheck yourself31 practice scenariosAnswers checked against the books and guidelines.

Sheet 01 · Cardiac31 / 31

That is Cardiac, all 31 cards.

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