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Perioperative Medicine

Sheet 06Anaesthesia

Perioperative Medicine

Proceed or postpone, which tests and medicines, fasting and sedation, laparoscopy and positioning, temperature and nausea, and the problems after surgery.

Cards
19
Minutes
about13
Scenarios
19

Start at card 1Review the rules

Core rulesRead these first2 cards · about 2 min

  1. 01Leaving recovery
  2. 02What the pneumoperitoneum and the tilt do

Leaving recovery

01 / 19

Leave recovery on a scored check of activity, breathing, circulation, consciousness and saturation.

Modified Aldrete score (Miller): each item scores 2, 1 or 0

Item2 · 1 · 0
Activity, open its explanationMoves all four limbs 2; two limbs 1; none 0
Respiration, open its explanationBreathes deeply, coughs freely 2; dyspnoea or limited 1; apnoeic 0
Circulation: pressure off pre‑anaesthetic baseline, open its explanationWithin 20% 2; 20%–49% 1; 50% or more 0
Consciousness, open its explanationFully awake 2; rousable on calling 1; not responding 0
Oxygen saturation, open its explanationAbove 92% on air 2; above 90% only with oxygen 1; lower 0
Total out of 10, open its explanation9 or more: fit for phase 1 discharge; pain, nausea not scored

Leaving the first stage and going home

FindingDecision
Awake, airway‑protecting, air saturation, pain and nausea controlled, open its explanationBypass first stage; send straight to second‑stage care
Phase 1 discharge, open its explanationOn the Aldrete score, not elapsed time
Obstructive sleep apnoea, general anaesthesia, Aldrete met, open its explanationObserve 60 more minutes
Obstructive sleep apnoea, extra 60 minutes observed, open its explanationDischarge once baseline room‑air saturation holds without respiratory events

After ambulatory surgery

After ambulatory surgeryCommonest
Delayed day‑surgery discharge: commonest cause, open its explanationNausea and vomiting in Barash; pain in Miller
Symptom persisting after discharge home, open its explanationDrowsiness, not sore throat, aches, or nausea and vomiting

Report a problem with card 1: Leaving recovery

What the pneumoperitoneum and the tilt do

02 / 19

Pneumoperitoneum lowers functional residual capacity (FRC) and compliance and raises afterload; the tilt moves preload.

ChangeEffect
CO2 pneumoperitoneum: lung mechanics and volumes, open its explanationCompliance, FRC and vital capacity fall
CO2 pneumoperitoneum: ventilation and airway, open its explanationV/Q mismatch and peak airway pressure rise
Insufflation: circulation, open its explanationSystemic vascular resistance (SVR), mean arterial pressure (MAP) and arterial CO2 rise; cardiac output falls
Insufflation: organ flow and pressures, open its explanationRenal, portal, splanchnic flow fall; airway pressure, intracranial pressure (ICP) rise
Head‑up tilt under anaesthesia, open its explanationPreload and stroke volume fall, SVR rises; heart rate rises
Steep head‑down tilt, euvolaemic, open its explanationLeg resistance falls; output rise fades; steep tilt lowers it

Report a problem with card 2: What the pneumoperitoneum and the tilt do

Part 1 · DecisionsWhat to do6 cards · about 4 min

  1. 03Proceed, postpone or investigate
  2. 04Which tests
  3. 05Regular medicines: hold or stop
  4. 06Fasting and antibiotic prophylaxis
  5. 07Sedation and office-based anaesthesia
  6. 08Preventing nausea and vomiting

Proceed, postpone or investigate

03 / 19

Postpone only for a finding that raises risk and can be improved before surgery.

American Society of Anesthesiologists (ASA) physical status classes (Miller)

ClassPatient
ASA 1, open its explanationNormal and healthy
ASA 2, open its explanationMild systemic disease
ASA 3, open its explanationSevere systemic disease
ASA 4, open its explanationSevere systemic disease that constantly threatens life
ASA 5, open its explanationMoribund: not expected to survive without the operation
ASA 6, open its explanationDeclared brain‑dead; organs being removed for donation
Suffix E, open its explanationEmergency surgery

Before elective surgery

Patient before elective surgeryDecision
Day‑of‑surgery hypertension, open its explanationPossibly situational: address anxiety, recheck properly
Rechecked blood pressure against 180/110, open its explanationBelow: proceed; at or above: weigh delay individually
Systolic under 180 and diastolic under 110 mmHg, open its explanationProceed; above, weigh optimisation against cost of delay
Scoliosis correction, good exercise tolerance, normal lung tests, open its explanationECG and echocardiogram: ventricular function, pulmonary pressures
Scoliosis correction, no lung tests yet, open its explanationPulmonary function tests first
History and examination older than 30 days, open its explanationRepeat it; valid only 30 days
Update after admission, before surgery, open its explanationWithin 24 hours of admission (Miller: 48 hours)
Previous stroke: what lowers the risk most, open its explanationDefer elective surgery; waiting 6 months beats a short delay
Previous stroke, existing antiplatelets, open its explanationContinue them: standard care, not the risk‑lowering step
Stroke the day before a booked operation, open its explanationDefer; of usual offers, only 12 months clears the 9‑month plateau

Sources: AHA/ACC 2024 · §6.7

Report a problem with card 3: Proceed, postpone or investigate

Which tests

04 / 19

Order tests for what the history and examination find, never by routine.

Which test for which patient

PatientTest
Fit, asymptomatic, elective surgery, open its explanationNo routine tests; only if history, examination, procedure indicate
Childbearing age, pregnancy not excluded, open its explanationConsented pregnancy test before any anaesthetic
Suspected obstructive sleep apnoea, open its explanationScreen with the STOP‑Bang questionnaire
Known obstructive sleep apnoea, open its explanationEstablish severity and positive airway pressure (PAP) settings, not screening

STOP-Bang questionnaire (Barash; risk bands Barash, Faust): one point per yes

ItemScores a point when
Snoring, open its explanationLoud snoring
Tiredness, open its explanationTired in the daytime
Observed, open its explanationApnoea, choking or gasping seen during sleep
Pressure, open its explanationHigh blood pressure
Body mass index (BMI), open its explanationAbove 35 kg/m²
Age, open its explanationOver 50 years
Neck, open its explanation40 cm either sex, or men 43 cm, women 41
Gender, open its explanationMale
Under 3, open its explanationLow risk
3–4, open its explanationIntermediate risk: the screen is positive (Miller calls 3 or more high)
5–8, open its explanationHigh risk: more severe sleep apnoea, more postoperative complications

Report a problem with card 4: Which tests

Regular medicines: hold or stop

05 / 19

Hold what harms on the day; stop anticoagulants by their clock; continue long-term steroids.

Diabetes tablets and anticoagulants: when to stop

MedicineBefore surgery
Non‑insulin antidiabetic tablets, open its explanationStop on the day; SGLT‑2 inhibitors earlier
Apixaban, open its explanationStop days ahead; at least 3 days before neuraxial block
Warfarin, open its explanationStop five days before; international normalised ratio (INR) day before; high‑risk: heparin

Long-term steroids

MedicineBefore surgery
Chronic corticosteroids in rheumatoid arthritis, open its explanationStress‑dose hydrocortisone if over 10 mg prednisone daily

Report a problem with card 5: Regular medicines: hold or stop

Fasting and antibiotic prophylaxis

06 / 19

Clear fluids to 2 hours; antibiotic within its window before incision, redosed when delayed.

Fasting

IntakeRule
Pulp‑free apple juice two hours before, open its explanationClear fluid: proceed with elective anaesthetic now
Clear fluids, children, open its explanation2 hours (ASA); European consensus 1 hour
Breast milk or formula, open its explanationBreast milk 4 hours; formula 6 hours

Antibiotic prophylaxis

Antibiotic or delayWhen to give it
Prophylactic antibiotic, open its explanationWithin 60 minutes before incision; any time in window
Vancomycin or fluoroquinolone, open its explanationWithin 120 minutes before incision
Surgery delayed hours after the dose, open its explanationFresh dose within 60 minutes before incision, not after

Report a problem with card 6: Fasting and antibiotic prophylaxis

Sedation and office-based anaesthesia

07 / 19

Sedation is a continuum: be ready to rescue a patient one level deeper than planned.

Levels of sedation

FindingLevel
Rousable only by repeated or painful stimulation, open its explanationDeep sedation: purposeful response still present
No response even to painful stimulation, open its explanationGeneral anaesthesia, not deep sedation
Ventilation unaffected versus may be impaired, open its explanationUnaffected: minimal sedation; may be impaired: deep sedation

Moderate sedation

FeatureWhat it means
Spontaneous ventilation in moderate sedation, open its explanationAdequate; needs no support
Airway reflexes in moderate sedation, open its explanationWeakened; added aspiration risk
Deadliest complication of moderate sedation, open its explanationOversedation compromising breathing

Before sedation

FindingAction
Alcohol or drug abuse history, open its explanationPredicts sedation failure; anaesthetist‑delivered deep sedation or general anaesthesia
Agitation before sedation, open its explanationExclude hypoxaemia, then physiological causes, before fear or pain

Office-based anaesthesia

Office-basedFact
Office procedure most linked to death, open its explanationAbdominoplasty, usually through pulmonary embolism
Most important office sedation monitor, open its explanationVigilant trained anaesthetist throughout; devices only supplement

Report a problem with card 7: Sedation and office-based anaesthesia

Preventing nausea and vomiting

08 / 19

Count the Apfel risk factors; prophylaxis grows with the count.

Apfel score for postoperative nausea and vomiting (PONV), consensus guideline and Miller

Risk factorPoints
Female sex, open its explanation1
Non‑smoker, open its explanation1
Prior PONV or motion sickness, open its explanation1
Postoperative opioids, open its explanation1, only when stated
Apfel score 0, 1, 2, open its explanation10%, 20%, 40% risk
Apfel score 3, 4, open its explanation60%, 80% risk

Weight of the risk factors

WeightRisk factor
Strongest single predictor, open its explanationFemale sex
Other independent risk factors, open its explanationPrior nausea or motion sickness, non‑smoking, younger age, opioids

High-risk plan

FindingPlan
Prior PONV, open its explanationPropofol total intravenous over volatile; multimodal antiemetics; regional blocks

Report a problem with card 8: Preventing nausea and vomiting

Part 2 · RecognitionWhat it is2 cards · about 1 min

  1. 09Laparoscopy on the monitors
  2. 10Fluid responsiveness on the monitor

Laparoscopy on the monitors

09 / 19

Read the monitors against the pneumoperitoneum: name the cause before treating.

Part 3 · SituationsWhat now5 cards · about 3 min

  1. 11Positioning: nerves and eyes
  2. 12Laparoscopy goes wrong
  3. 13Temperature
  4. 14Nausea in recovery
  5. 15After surgery: the common problems

Positioning: nerves and eyes

11 / 19

Pad and position to protect nerves and eyes; sudden visual loss needs urgent ophthalmology review.

Nerves at risk

PositionNerve
Lithotomy: commonest motor nerve injury, open its explanationCommon peroneal, also called common fibular
Lithotomy: commonest nerve injury, prospective all‑neuropathy count, open its explanationObturator, 50 per 10,000; peroneal 30 per 10,000
Cycling or long‑standing upper‑arm BP cuff, open its explanationRadial nerve at greatest risk; move cuff periodically

Beach-chair and prone set-up

PositionSet-up
Beach‑chair: arterial transducer level, open its explanationZero at the external ear
Beach‑chair: BP cuff site, open its explanationArm, never the leg
Prone chest supports, open its explanationBelow axillae, clavicle to iliac crest; globes pressure‑free

Visual loss after prone spine surgery

PointWhat to know
First step, open its explanationInspect eyes at bedside; immediate ophthalmology assessment; never wait
Likeliest cause, open its explanationPosterior ischaemic optic neuropathy; retinal artery occlusion needs globe pressure

Intraocular pressure

PressuresValues
Intraocular pressure: normal, pathological, posture rise, open its explanation12–20 (16 ± 5); >25 pathological; posture adds ≤6 mmHg

Report a problem with card 11: Positioning: nerves and eyes

Laparoscopy goes wrong

12 / 19

Find the true cause first; release pneumoperitoneum when it threatens circulation, oxygenation or heart rhythm.

Event during laparoscopy

Event during laparoscopyAction
Subcutaneous emphysema with hypercarbia alone, open its explanationHyperventilate; desufflate only if inadequate
Emphysema plus hypotension, hypoxia or high airway pressure, open its explanationTension capnothorax: desufflate now, support circulation, decompress if severe
Hypotension despite fluid and pressor, failing heart, open its explanationReduce or release pneumoperitoneum, not more pressor or fluid
Desaturation soon after head‑down tilt, open its explanationSuspect endobronchial tube; auscultate both sides, withdraw tube
Bradycardia or asystole as insufflation begins, open its explanationDeflate; prevent with slow insufflation, lower pressure, glycopyrrolate

The mechanism behind each event

EventMechanism
Blood pressure falls when positive end‑expiratory pressure (PEEP) raised, open its explanationReduced venous return
Oliguria during pneumoperitoneum, open its explanationRaised abdominal pressure plus vasopressin release, not hypovolaemia
Bradycardia or asystole as insufflation begins, open its explanationVagal reflex from peritoneal stretch
Tachycardia minutes after rapid desflurane step‑up, open its explanationDesflurane sympathetic surge; hypercarbia comes later

Report a problem with card 12: Laparoscopy goes wrong

Temperature

13 / 19

Core temperature falls first by redistribution; heat then leaves mainly by radiation and convection.

How heat is lost

SettingMain route
CO2 insufflation in laparoscopy, open its explanationConvection
Main heat loss after first hour, open its explanationRadiation and convection; evaporation, conduction minor

Phases of core cooling

TimePhase
First hour: core temperature falls, open its explanationRedistribution from core to periphery
3 to 5 hours, open its explanationPlateau: heat loss equals heat production

Mild hypothermia: prevention and harm

PointFact
Single best prevention, open its explanationActive forced‑air skin warming; room, fluid warming only add
Harm of mild perioperative hypothermia, open its explanationCatecholamines, infection, bleeding, cardiac events, longer stay

Postoperative shivering

FindingTreatment
Low core temperature, open its explanationRewarm
Normothermia, open its explanationPethidine first; clonidine or other opioids also work

Report a problem with card 13: Temperature

Nausea in recovery

14 / 19

Rescue with a different class from the prophylaxis; match the drug to the patient.

After surgery: the common problems

15 / 19

After surgery, name the commonest cause or fix: each problem has its own risk set.

Delirium

DeliriumDetail
Baseline risk factors, open its explanationOver 65, cognitive impairment, hearing or visual loss, ASA III+
Further risk factors, open its explanationLow albumin, dehydration, sleep deprivation, immobilisation
Prevention in frail elderly, open its explanationTitrate to processed EEG, avoid burst suppression; depth over technique
Daily drinker: agitation, tachycardia 24+ hours abstinent, open its explanationAlcohol withdrawal: small titrated benzodiazepine doses first‑line

Low oxygen and low urine output

ProblemLikeliest cause
Day‑one hypoxaemia after cervical cord injury or fixation, open its explanationAtelectasis
Postoperative oliguria, open its explanationUsually hypovolaemia
Oliguria despite fluid after long bariatric surgery, open its explanationSuspect rhabdomyolysis; keep hydrating

Urinary retention: risk factors

GroupRisk factors
Demographic, open its explanationMale sex, older age
Surgical, open its explanationLong operations, joint replacement, perineal surgery
Fluid and anaesthetic, open its explanationGenerous fluids, neuraxial local anaesthetic or opioid

Report a problem with card 15: After surgery: the common problems

Part 4 · Conditions and mechanismsWhy it is true3 cards · about 2 min

  1. 16Clots, cement and hip fracture
  2. 17Pulmonary risk and outcome
  3. 18Laparoscopy: the gas and cardiopulmonary disease

Clots, cement and hip fracture

16 / 19

Major surgery carries clot risk, orthopaedic surgery adds cement, and age drives death after hip fracture.

Venous thromboembolism: the risk

SettingRisk
Hip or knee replacement, hip fracture surgery, open its explanationOne top VTE‑risk band
Top band without drug prophylaxis, open its explanationDeep vein thrombosis (DVT) in 40% to 80%
Forced single pick for DVT, open its explanationKnee replacement

Venous thromboembolism: prevention

MeasureEffect
Regional anaesthesia lowers DVT: joint named by Miller, open its explanationHip replacement; knee shares benefit, no source ranks them
Prophylaxis after hip/knee replacement, hip fracture, open its explanationLow‑molecular‑weight heparin (LMWH); direct oral anticoagulant (DOAC) acceptable
Aspirin alone as prophylaxis, open its explanationChest physicians' guideline accepts it; Stoelting: low‑risk surgery only

Bone cement implantation syndrome

PointFact
Highest‑risk procedure, open its explanationLong cemented femoral stem; worse: pathological fracture, pulmonary hypertension
Signs at cementation, open its explanationHypoxaemia and hypotension; both fall, not rise
Reducing embolism before femoral prosthesis insertion, open its explanationPulse‑lavage medullary canal, drill distal vent hole

Named operations: the leading hazard

OperationLeading hazard
Living kidney donor nephrectomy, open its explanationPulmonary embolism: mechanical plus heparin prophylaxis until walking
Hip fracture repair: major predictor of death, open its explanationAdvanced age; cardiac disease is a lesser predictor
Hip fracture repair: in‑hospital mortality, open its explanationLow single digits (US 3.9%, UK 6.6%); one‑year several‑fold higher

Report a problem with card 16: Clots, cement and hip fracture

Pulmonary risk and outcome

17 / 19

Smoking, lung disease and the operation site predict pulmonary complications; analgesia changes outcome.

What raises risk

FactorEffect
Smoking, open its explanationRaises ischaemic cardiac, pulmonary, wound risk; weakens macrophage, ciliary defences
Abdominal or thoracic operation site, open its explanationOutright postoperative pulmonary complication risk factor
Any smoking or advanced age, open its explanationAlso risk factors; only cut‑off: over 60 pack‑years doubles risk

What lowers risk

FactorEffect
Smoking and PONV, open its explanationLowers PONV risk; never offsets the other harms
Postoperative thoracic epidural after major abdominal surgery, open its explanationMay cut myocardial infarction; continue it, not removed

Sources: AHA/ACC 2024 · §8.2

Report a problem with card 17: Pulmonary risk and outcome

Laparoscopy: the gas and cardiopulmonary disease

18 / 19

Absorbed carbon dioxide must be breathed off; sick hearts and lungs bear it worst.

The gas and where it leaks

PointFact
Gas for pneumoperitoneum, open its explanationCarbon dioxide; never insufflate oxygen
Capnothorax: injury causes, open its explanationDiaphragm or falciform ligament injury
Capnothorax: other causes and risk site, open its explanationCongenital diaphragmatic channels, extraperitoneal tracking; worst near diaphragm

Heart and lung disease

SituationPlan
Chronic obstructive pulmonary disease (COPD) under carbon dioxide pneumoperitoneum, open its explanationChief threat: absorbed CO2 load; V/Q mismatch is secondary
Insufflation in cardiopulmonary disease, open its explanationFlat; pressure 12–15 mmHg, lowest giving exposure; deepen for hypertension

Before entry

StepPurpose
Orogastric tube before laparoscopic entry, open its explanationEmpties stomach; protects it from needle and trocar injury

Report a problem with card 18: Laparoscopy: the gas and cardiopulmonary disease

TrapsCheck these before you finish1 card · about 1 min

  1. 19Traps

Traps

19 / 19

The tempting choice is the familiar one; the books often name another.

TemptingRight call
Obturator nerve injury after lithotomy, open its explanationCommon peroneal (fibular): commonest motor injury; obturator, one all‑neuropathy count
Cancelling for day‑of‑surgery hypertension, open its explanationAddress anxiety, recheck; proceed below 180/110, else weigh delay
Repeat ondansetron after failed prophylaxis, open its explanationNew‑class rescue; same‑class repeat within 6 hours adds nothing
CO2 embolism for asystole at insufflation, open its explanationVagal reflex from peritoneal stretch: deflate the abdomen
Radiation and conduction as main heat loss, open its explanationRadiation and convection; conduction and evaporation contribute little
Evaporation as insufflation heat loss, open its explanationConvection: cold, dry gas carries heat from peritoneal contents
Worse V/Q mismatch in COPD pneumoperitoneum, open its explanationAbsorbed CO2 load the diseased lungs cannot clear
Extra delay: pulp‑free apple juice two hours ago, open its explanationClear fluid; two‑hour interval met, proceed
Central retinal artery compression after prone spine surgery, open its explanationPosterior ischaemic optic neuropathy, unless the globe was pressed

Report a problem with card 19: Traps

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QuizCheck yourself19 practice scenariosAnswers checked against the books and guidelines.

Sheet 06 · Perioperative Medicine19 / 19

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